Literature DB >> 1167565

Polymorphonuclear leukocytes in antibody-dependent cellular cytotoxicity.

R P Gale, J Zighelboim.   

Abstract

Human polymorphonuclear leukocytes (PMN) lyse antibody-coated target cells in an immunologically specific fashion--antibody-dependent cellular cytotoxicity (ADCC). PMN-mediated cytolysis is independent of complement, de novo protein synthesis, and DNA replication. Cytolysis is rapid, detectable at low PMN:target cell ratios, and exceeds lymphocyte-mediated ADCC. The interaction appears to be mediated via an Fc receptor and is inhibited by aggregated gamma-globulin. A role for PMN in host tumor cell immunity is discussed.

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Year:  1975        PMID： 1167565

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  47 in total

1.  Neutrophil-mediated cytotoxicity triggered by immune complexes: the role of reactive oxygen metabolites.

Authors:  J R Geffner; M Giordano; M S Palermo; A Prat; G P Serebrinsky; M A Isturiz
Journal:  Clin Exp Immunol       Date:  1987-09       Impact factor: 4.330

2.  Mechanisms of resistant of herpesviruses: comparison of the effectiveness of different cell types in mediating antibody-dependent cell-mediated cytotoxicity.

Authors:  A S Grewal; B T Rouse; L A Babiuk
Journal:  Infect Immun       Date:  1977-03       Impact factor: 3.441

3.  Enhancement of antibody-dependent cell-mediated cytotoxicity of herpesvirus-infected cells by complement.

Authors:  B T Rouse; A S Grewal; L A Babiuk; Y Fujimiya
Journal:  Infect Immun       Date:  1977-12       Impact factor: 3.441

4.  The effects of halothane anaesthesia on antibody-dependent cellular cytotoxicity in rats.

Authors:  B M Vose; I Kimber
Journal:  Immunology       Date:  1977-05       Impact factor: 7.397

5.  Human bone marrow lymphocytes. Cytotoxic effector cells in the bone marrow of normal individuals.

Authors:  A S Fauci; J E Balow; K R Pratt
Journal:  J Clin Invest       Date:  1976-04       Impact factor: 14.808

6.  Activation of triggering receptor expressed on myeloid cells-1 on human neutrophils by marburg and ebola viruses.

Authors:  Mansour Mohamadzadeh; Sadie S Coberley; Gene G Olinger; Warren V Kalina; Gordon Ruthel; Claudette L Fuller; Dana L Swenson; William D Pratt; Douglas B Kuhns; Alan L Schmaljohn
Journal:  J Virol       Date:  2006-07       Impact factor: 5.103

7.  Quantitative and qualitative effects of cyclophosphamide administration on circulating polymorphonuclear leucocytes.

Authors:  G W Hunninghake; A S Fauci
Journal:  Immunology       Date:  1976-07       Impact factor: 7.397

8.  Human monocyte antibody-dependent cell-mediated cytotoxicity to tumor cells.

Authors:  G M Shaw; P C Levy; A F LoBuglio
Journal:  J Clin Invest       Date:  1978-12       Impact factor: 14.808

9.  Mechanisms of tumour cell destruction by PMA-activated human neutrophils.

Authors:  F Dallegri; G Frumento; F Patrone
Journal:  Immunology       Date:  1983-02       Impact factor: 7.397

10.  Reversal of immune complex inhibition of antibody-dependent cell-mediated cytotoxicity by normal human serum.

Authors:  M A Isturiz; S B Fink; M M de Bracco
Journal:  Clin Exp Immunol       Date:  1982-06       Impact factor: 4.330
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