| Literature DB >> 11673162 |
K M Gosche1, J A Mortimer, C D Smith, W R Markesbery, D A Snowdon.
Abstract
We describe an automated volumetric measure of the hippocampus obtained with software called the Knowledge-Guided MRI Analysis Program (KGMAP). Postmortem MR images from 56 participants in the Nun Study were used to validate the measure. KGMAP-determined volumes strongly correlated with those obtained with manual tracings and neurofibrillary pathologic findings of Alzheimer disease in the hippocampus. KGMAP provides a rapid and accurate estimate of hippocampal volume that is suitable for use in clinical practice.Entities:
Mesh:
Year: 2001 PMID: 11673162 PMCID: PMC7974428
Source DB: PubMed Journal: AJNR Am J Neuroradiol ISSN: 0195-6108 Impact factor: 3.825