Literature DB >> 11671995

Titanocene-Catalyzed Reduction of Lactones to Lactols.

Xavier Verdaguer1, Marcus C. Hansen, Scott C. Berk, Stephen L. Buchwald.   

Abstract

A convenient method for the conversion of lactones to lactols is described. The hydrosilylation to lactols is carried out via air-stable titanocene difluoride or a titanocene diphenoxide precatalyst using inexpensive polymethylhydrosiloxane (PMHS) as the stoichiometric reductant. These procedures have been demonstrated with a variety of substrates and proceed in good to excellent yield.

Entities:  

Year:  1997        PMID： 11671995     DOI： 10.1021/jo971560s

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

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Authors:  Cesar Gonzalez; Sam Kavoosi; Andersson Sanchez; Stanislaw F Wnuk
Journal:  Carbohydr Res       Date:  2016-06-11       Impact factor: 2.104

3.  Chemo-Enzymatic Synthesis of Optically Active γ- and δ-Decalactones and Their Effect on Aphid Probing, Feeding and Settling Behavior.

Authors:  Filip Boratyński; Katarzyna Dancewicz; Marlena Paprocka; Beata Gabryś; Czesław Wawrzeńczyk
Journal:  PLoS One       Date:  2016-01-07       Impact factor: 3.240
  3 in total

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