| Literature DB >> 11671754 |
Mitsuhiro Arisawa1, Yasuhiro Torisawa, Michiaki Kawahara, Masamichi Yamanaka, Atsushi Nishida, Masako Nakagawa.
Abstract
An efficient synthesis of alpha,beta-unsaturated ketones by the reaction of acid chlorides with trialkylaluminum (1/3 mole equiv) in the presence of AlCl(3) (1 mol equiv) is described. Dialkylzincs were also useful and are easier to prepare than trialkylaluminum. Reaction of RCOCl with R'AlCl(2) or R'(2)AlCl gave R'COR, without AlCl(3), in high yield.Entities:
Year: 1997 PMID： 11671754 DOI： 10.1021/jo970244a
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354