Literature DB >> 11671513

Intramolecular Diels-Alder Reaction of 2-Cyano-1-aza-1,3-butadienes.

Nicholas J. Sisti1, Emmanuel Zeller, David S. Grierson, Frank W. Fowler.   

Abstract

It has been demonstrated that a 2-cyano substituent is sufficient to activate 1-aza-1,3-butadienes with respect to the intramolecular Diels-Alder reaction. This reaction is successful for the preparation of the indolizidine and quinolizidine ring systems. The stereochemistry of the isomeric products was assigned by a careful analysis of their NMR spectral data.

Entities:  

Year:  1997        PMID: 11671513     DOI: 10.1021/jo961403d

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

1.  Chemo- and Stereoselective Transition-Metal-Free Amination of Amides with Azides.

Authors:  Veronica Tona; Aurélien de la Torre; Mohan Padmanaban; Stefan Ruider; Leticia González; Nuno Maulide
Journal:  J Am Chem Soc       Date:  2016-06-28       Impact factor: 15.419

  1 in total

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