Literature DB >> 11668416

Combined quantitative (1)H and (13)C nuclear magnetic resonance spectroscopy for characterization of heparin preparations.

M Guerrini1, A Bisio, G Torri.   

Abstract

The sulfation patterns of pig and bovine mucosal commercial heparin preparations can be characterized and distinguished from each other easily by analysis of their monodimensional proton and carbon nuclear magnetic resonance ((1)H and (13)C-NMR) spectra. NMR spectroscopy can detect and quantify signals associated with major sequences as well as with minor residues such as the typical ones associated with the antithrombin (AT) binding sequence and the "linkage region." Contaminants arising from industrial preparation processes are also detectable.

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Year:  2001        PMID： 11668416     DOI： 10.1055/s-2001-17958

Source DB:  PubMed          Journal:  Semin Thromb Hemost        ISSN： 0094-6176            Impact factor:   4.180


  12 in total

1.  Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events.

Authors:  Marco Guerrini; Daniela Beccati; Zachary Shriver; Annamaria Naggi; Karthik Viswanathan; Antonella Bisio; Ishan Capila; Jonathan C Lansing; Sara Guglieri; Blair Fraser; Ali Al-Hakim; Nur Sibel Gunay; Zhenqing Zhang; Luke Robinson; Lucinda Buhse; Moheb Nasr; Janet Woodcock; Robert Langer; Ganesh Venkataraman; Robert J Linhardt; Benito Casu; Giangiacomo Torri; Ram Sasisekharan
Journal:  Nat Biotechnol       Date:  2008-04-23       Impact factor: 54.908

2.  Scientific considerations in the review and approval of generic enoxaparin in the United States.

Authors:  Sau Lee; Andre Raw; Lawrence Yu; Robert Lionberger; Naiqi Ya; Daniela Verthelyi; Amy Rosenberg; Steve Kozlowski; Keith Webber; Janet Woodcock
Journal:  Nat Biotechnol       Date:  2013-03       Impact factor: 54.908

3.  Control of the heparosan N-deacetylation leads to an improved bioengineered heparin.

Authors:  Zhenyu Wang; Bo Yang; Zhenqing Zhang; Mellisa Ly; Majde Takieddin; Shaker Mousa; Jian Liu; Jonathan S Dordick; Robert J Linhardt
Journal:  Appl Microbiol Biotechnol       Date:  2011-04-12       Impact factor: 4.813

4.  Response surface optimization of the heparosan N-deacetylation in producing bioengineered heparin.

Authors:  Zhenyu Wang; Jennifer Li; Samantha Cheong; Ujjwal Bhaskar; Onishi Akihiro; Fuming Zhang; Jonathan S Dordick; Robert J Linhardt
Journal:  J Biotechnol       Date:  2011-09-10       Impact factor: 3.307

5.  Binding ability of methylene blue with heparin dependent on its sulfate level rather than its sulfation location or basic saccharide structure.

Authors:  Shi-Xi Jia; Qiao-Na Chi; Yuanyuan Zhang; Tao Liu; Xinhui Kou; Fanye Wang; Yun-Kun Qi; Shan-Shan Du; Xin-Hui Xing
Journal:  Glycoconj J       Date:  2021-09-13       Impact factor: 2.916

6.  Profiling glycol-split heparins by high-performance liquid chromatography/mass spectrometry analysis of their heparinase-generated oligosaccharides.

Authors:  Anna Alekseeva; Benito Casu; Giangiacomo Torri; Sabrina Pierro; Annamaria Naggi
Journal:  Anal Biochem       Date:  2012-11-29       Impact factor: 3.365

Review 7.  Heparin and heparan sulfate: analyzing structure and microheterogeneity.

Authors:  Zachary Shriver; Ishan Capila; Ganesh Venkataraman; Ram Sasisekharan
Journal:  Handb Exp Pharmacol       Date:  2012

8.  A new approach for heparin standardization: combination of scanning UV spectroscopy, nuclear magnetic resonance and principal component analysis.

Authors:  Marcelo A Lima; Timothy R Rudd; Eduardo H C de Farias; Lyvia F Ebner; Tarsis F Gesteira; Lauro M de Souza; Aline Mendes; Carolina R Córdula; João R M Martins; Debra Hoppensteadt; Jawed Fareed; Guilherme L Sassaki; Edwin A Yates; Ivarne L S Tersariol; Helena B Nader
Journal:  PLoS One       Date:  2011-01-18       Impact factor: 3.240

9.  The non-anticoagulant heparin-like K5 polysaccharide derivative K5-N,OSepi attenuates myocardial ischaemia/reperfusion injury.

Authors:  Massimo Collino; Collino Massimo; Alessandro Pini; Pini Alessandro; Rosanna Mastroianni; Mastroianni Rosanna; Elisa Benetti; Benetti Elisa; Cecilia Lanzi; Lanzi Cecilia; Daniele Bani; Bani Daniele; Chini Jacopo; Marco Manoni; Manoni Marco; Roberto Fantozzi; Fantozzi Roberto; Emanuela Masini; Masini Emanuela
Journal:  J Cell Mol Med       Date:  2012-09       Impact factor: 5.310

10.  Bovine and porcine heparins: different drugs with similar effects on human haemodialysis.

Authors:  Ana M F Tovar; Lisandra A C Teixeira; Simone M Rembold; Maurilo Leite; Jocemir R Lugon; Paulo A S Mourão
Journal:  BMC Res Notes       Date:  2013-06-13
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