Literature DB >> 11665321

Sex differences in genetic and environmental factors contributing to body-height.

K Silventoinen1, J Kaprio, E Lahelma, R J Viken, R J Rose.   

Abstract

Sex differences in the heritability of self-reported body-height in two Finnish twin cohorts were studied by using sex-limitation models. The first cohort was born in 1938-1949 (N = 4873 twin pairs) and the second in 1975-1979 (N = 2374 twin pairs). Body-height was greater in the younger cohort (difference of 3.1 cm for men and 2.9 cm for women). The heritability estimates were higher among men (h2 = 0.87 in the older cohort and h2 = 0.82 in the younger cohort) than women (h2 = 0.78 and h2 = 0.67, respectively). Sex-specific genetic factors were not statistically significant in either cohort, suggesting that the same genes contribute to variation in body height for both men and women. The stronger contribution of environmental factors to body-height among women questions the hypothesis that women are better buffered against environmental stress, at least for this phenotype.

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Year:  2001        PMID: 11665321     DOI: 10.1375/1369052012119

Source DB:  PubMed          Journal:  Twin Res        ISSN: 1369-0523


  6 in total

1.  Modeling genetic and environmental factors to increase heritability and ease the identification of candidate genes for birth weight: a twin study.

Authors:  M Gielen; P J Lindsey; C Derom; H J M Smeets; N Y Souren; A D C Paulussen; R Derom; J G Nijhuis
Journal:  Behav Genet       Date:  2007-12-22       Impact factor: 2.805

2.  The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.

Authors:  Jianhua Zhao; Mingyao Li; Jonathan P Bradfield; Haitao Zhang; Frank D Mentch; Kai Wang; Patrick M Sleiman; Cecilia E Kim; Joseph T Glessner; Cuiping Hou; Brendan J Keating; Kelly A Thomas; Maria L Garris; Sandra Deliard; Edward C Frackelton; F George Otieno; Rosetta M Chiavacci; Robert I Berkowitz; Hakon Hakonarson; Struan F A Grant
Journal:  BMC Med Genet       Date:  2010-06-14       Impact factor: 2.103

3.  Genetic and environmental influences on skeletal muscle phenotypes as a function of age and sex in large, multigenerational families of African heritage.

Authors:  Steven J Prior; Stephen M Roth; Xiaojing Wang; Candace Kammerer; Iva Miljkovic-Gacic; Clareann H Bunker; Victor W Wheeler; Alan L Patrick; Joseph M Zmuda
Journal:  J Appl Physiol (1985)       Date:  2007-07-26

4.  Age at adiposity rebound: determinants and association with nutritional status and the metabolic syndrome at adulthood.

Authors:  S Péneau; R González-Carrascosa; G Gusto; D Goxe; O Lantieri; L Fezeu; S Hercberg; M F Rolland-Cachera
Journal:  Int J Obes (Lond)       Date:  2016-03-22       Impact factor: 5.095

5.  Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis.

Authors: 
Journal:  Int J Epidemiol       Date:  2012-07-23       Impact factor: 7.196

6.  Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts.

Authors:  Aline Jelenkovic; Reijo Sund; Yoon-Mi Hur; Yoshie Yokoyama; Jacob V B Hjelmborg; Sören Möller; Chika Honda; Patrik K E Magnusson; Nancy L Pedersen; Syuichi Ooki; Sari Aaltonen; Maria A Stazi; Corrado Fagnani; Cristina D'Ippolito; Duarte L Freitas; José Antonio Maia; Fuling Ji; Feng Ning; Zengchang Pang; Esther Rebato; Andreas Busjahn; Christian Kandler; Kimberly J Saudino; Kerry L Jang; Wendy Cozen; Amie E Hwang; Thomas M Mack; Wenjing Gao; Canqing Yu; Liming Li; Robin P Corley; Brooke M Huibregtse; Catherine A Derom; Robert F Vlietinck; Ruth J F Loos; Kauko Heikkilä; Jane Wardle; Clare H Llewellyn; Abigail Fisher; Tom A McAdams; Thalia C Eley; Alice M Gregory; Mingguang He; Xiaohu Ding; Morten Bjerregaard-Andersen; Henning Beck-Nielsen; Morten Sodemann; Adam D Tarnoki; David L Tarnoki; Ariel Knafo-Noam; David Mankuta; Lior Abramson; S Alexandra Burt; Kelly L Klump; Judy L Silberg; Lindon J Eaves; Hermine H Maes; Robert F Krueger; Matt McGue; Shandell Pahlen; Margaret Gatz; David A Butler; Meike Bartels; Toos C E M van Beijsterveldt; Jeffrey M Craig; Richard Saffery; Lise Dubois; Michel Boivin; Mara Brendgen; Ginette Dionne; Frank Vitaro; Nicholas G Martin; Sarah E Medland; Grant W Montgomery; Gary E Swan; Ruth Krasnow; Per Tynelius; Paul Lichtenstein; Claire M A Haworth; Robert Plomin; Gombojav Bayasgalan; Danshiitsoodol Narandalai; K Paige Harden; Elliot M Tucker-Drob; Timothy Spector; Massimo Mangino; Genevieve Lachance; Laura A Baker; Catherine Tuvblad; Glen E Duncan; Dedra Buchwald; Gonneke Willemsen; Axel Skytthe; Kirsten O Kyvik; Kaare Christensen; Sevgi Y Öncel; Fazil Aliev; Finn Rasmussen; Jack H Goldberg; Thorkild I A Sørensen; Dorret I Boomsma; Jaakko Kaprio; Karri Silventoinen
Journal:  Sci Rep       Date:  2016-06-23       Impact factor: 4.379

  6 in total

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