Literature DB >> 1166074

Hydroxyurea-induced erythroid differentiation.

N J Rencricca, B S Morse, F C Monette, D Howard, F Stohlman.   

Abstract

Hydroxyurea, a cytotoxic agent which destroys cells in DNA synthesis, has been shown to evoke the differentiation of a small number of hemopoietic precursor cells in the erythroid series of erythropoietically suppressed hypertransfused mice. This effect does not appear to be mediated by erythropoietin (EP) since the simultaneous injection of anti-EP did not alter this response.

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Year:  1975        PMID: 1166074     DOI: 10.3181/00379727-149-38956

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  3 in total

1.  Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesis.

Authors:  N L Letvin; D C Linch; G P Beardsley; K W McIntyre; B A Miller; D G Nathan
Journal:  J Clin Invest       Date:  1985-06       Impact factor: 14.808

2.  Migration of lymphoid cells to the bone marrow of rat following eradication of cells in DNA synthesis and in mitosis.

Authors:  Z Ben-Ishay; F Reichert; S Sharon
Journal:  Experientia       Date:  1978-10-15

3.  Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.

Authors:  O S Platt; S H Orkin; G Dover; G P Beardsley; B Miller; D G Nathan
Journal:  J Clin Invest       Date:  1984-08       Impact factor: 14.808

  3 in total

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