Literature DB >> 1166069

Suppression of lymphocyte transformation by 16, (16) dimethyl prostaglandin E2 and unsaturated fatty acids.

A A Mihas, R G Gibson, B I Hirschowitz.   

Abstract

A new synthetic prostaglandin (16, 16-PGE2) and unsaturated fatty acids have been shown to inhibit the incorporation of [3H]thymidine in the lymphocyte transformation reaction in response to phytohemagglutinin (PHA). This inhibition was not due to toxicity of these substances, for the lymphocytes remained intact and capable of excluding trypan blue.

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Year:  1975        PMID: 1166069     DOI: 10.3181/00379727-149-38949

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  11 in total

1.  Inhibition of lymphocyte proliferation stimulated by lectins and allogeneic cells by normal plasma lipoproteins.

Authors:  J H Morse; L D Witte; D S Goodman
Journal:  J Exp Med       Date:  1977-12-01       Impact factor: 14.307

Review 2.  Biologically active products from African Trypanosomes.

Authors:  I Tizard; K H Nielsen; J R Seed; J E Hall
Journal:  Microbiol Rev       Date:  1978-12

3.  The effect of free fatty acids on spectrin organization in lymphocytes.

Authors:  F D Stephen; S J Yokota; E A Repasky
Journal:  Cell Biophys       Date:  1990-12

4.  The spleen is required for the suppression of experimental allergic encephalomyelitis by prostaglandin precursors.

Authors:  J Mertin; A Stackpoole
Journal:  Clin Exp Immunol       Date:  1979-06       Impact factor: 4.330

5.  Enhancement of lymphocyte blastogenic and delayed hypersensitivity skin responses by indomethacin.

Authors:  C C Muscoplat; P M Rakich; C O Thoen; D W Johnson
Journal:  Infect Immun       Date:  1978-06       Impact factor: 3.441

6.  Inhibition of lymphocyte capping by fatty acids in mouse and man.

Authors:  E A Santiago-Delpín; A A Román-Franco; J I Colón
Journal:  Lipids       Date:  1982-10       Impact factor: 1.880

7.  Regulation of mitogen- and antigen-stimulated lymphocyte blastogenesis by prostaglandins.

Authors:  C C Muscoplat; D J Klausner; C J Brunner; E D Sloane; D W Johnson
Journal:  Infect Immun       Date:  1979-10       Impact factor: 3.441

8.  Effect of essential fatty acids on circulating T cell subsets in patients with colorectal cancer.

Authors:  P Purasiri; J Ashby; S D Heys; O Eremin
Journal:  Cancer Immunol Immunother       Date:  1994-10       Impact factor: 6.968

9.  Dietary lipid modulation of immune responsiveness.

Authors:  K L Erickson; D A Adams; C J McNeill
Journal:  Lipids       Date:  1983-07       Impact factor: 1.880

10.  Inhibition of complement-dependent rosette formation after lymphocyte incubation with fatty acids.

Authors:  M Papamichail; G Tsokos; M B Pepys; C Weyman; J Belin; A D Smith
Journal:  Immunology       Date:  1979-09       Impact factor: 7.397

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