Literature DB >> 1165547

Purine and pyrimidine transport in Schistosoma mansoni.

M G Levy, C P Read.   

Abstract

The uptake of purines and pyrimidines by adults of Schistosoma mansoni was studied. Cytosine, thymine, and uracil entered the worms entirely by diffusion. Adenine, guanine, hypoxanthine, and the nucleosides adenosine and uridine were absorbed in part by mediated systems. The results of inhibitor studies suggest the presence of 5 distinct transport sites for these latter compounds. The interaction of adenosine monophosphate with these sites was also studied.

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Year:  1975        PMID： 1165547

Source DB:  PubMed          Journal:  J Parasitol        ISSN： 0022-3395            Impact factor:   1.276


  12 in total

Review 1.  Pyrimidine metabolism in schistosomes: A comparison with other parasites and the search for potential chemotherapeutic targets.

Authors:  Mahmoud H El Kouni
Journal:  Comp Biochem Physiol B Biochem Mol Biol       Date:  2017-07-21       Impact factor: 2.231

2.  Schistosomes can hydrolyze proinflammatory and prothrombotic polyphosphate (polyP) via tegumental alkaline phosphatase, SmAP.

Authors:  Manal Elzoheiry; Akram A Da'dara; Catherine S Nation; Samar N El-Beshbishi; Patrick J Skelly
Journal:  Mol Biochem Parasitol       Date:  2019-05-30       Impact factor: 1.759

3.  Schistosome apyrase SmATPDase1, but not SmATPDase2, hydrolyses exogenous ATP and ADP.

Authors:  Akram A Da'dara; Rita Bhardwaj; Patrick J Skelly
Journal:  Purinergic Signal       Date:  2014-06-04       Impact factor: 3.765

4.  Characterization of schistosome tegumental alkaline phosphatase (SmAP).

Authors:  Rita Bhardwaj; Patrick J Skelly
Journal:  PLoS Negl Trop Dis       Date:  2011-04-05

5.  Schistosome tegumental ecto-apyrase (SmATPDase1) degrades exogenous pro-inflammatory and pro-thrombotic nucleotides.

Authors:  Akram A Da'dara; Rita Bhardwaj; Yasser B M Ali; Patrick J Skelly
Journal:  PeerJ       Date:  2014-03-18       Impact factor: 2.984

Review 6.  Schistosome feeding and regurgitation.

Authors:  Patrick J Skelly; Akram A Da'dara; Xiao-Hong Li; William Castro-Borges; R Alan Wilson
Journal:  PLoS Pathog       Date:  2014-08-14       Impact factor: 6.823

Review 7.  Purinergic signaling in schistosomal infection.

Authors:  Claudia Lucia Martins Silva
Journal:  Biomed J       Date:  2016-11-03       Impact factor: 4.910

8.  Long non-coding RNA levels can be modulated by 5-azacytidine in Schistosoma mansoni.

Authors:  Murilo S Amaral; Lucas F Maciel; Gilbert O Silveira; Giovanna G O Olberg; João V P Leite; Lucas K Imamura; Adriana S A Pereira; Patricia A Miyasato; Eliana Nakano; Sergio Verjovski-Almeida
Journal:  Sci Rep       Date:  2020-12-09       Impact factor: 4.379

9.  Intravascular Schistosoma mansoni Cleave the Host Immune and Hemostatic Signaling Molecule Sphingosine-1-Phosphate via Tegumental Alkaline Phosphatase.

Authors:  Manal Elzoheiry; Akram A Da'dara; Rita Bhardwaj; Qiang Wang; Manar S Azab; El-Saeed I El-Kholy; Samar N El-Beshbishi; Patrick J Skelly
Journal:  Front Immunol       Date:  2018-07-30       Impact factor: 7.561

10.  The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities.

Authors:  Kathrin K Geyer; Sabrina E Munshi; Martin Vickers; Michael Squance; Toby J Wilkinson; Daniel Berrar; Cristian Chaparro; Martin T Swain; Karl F Hoffmann
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2018-04-01       Impact factor: 4.077
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