| Literature DB >> 1164512 |
R G Schneider, R J Atkins, T S Hosty, G Tomlin, R Casey, H Lehmann, P A Lorkin, K Nagai.
Abstract
A new haemoglobin variant with a decreased oxygen affinity is described, in which the substitution, alpha 94 (G1) Asp replaced by Asn, affects the alpha1beta2 contact alpha1G1-beta2G4. The relevance of this variant to our understanding of the importance of the hydrogen bond between alpha1G1 and beta2G4 in Perutz's model of oxyhaemoglobin A is discussed.Entities:
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Year: 1975 PMID: 1164512
Source DB: PubMed Journal: Biochim Biophys Acta ISSN: 0006-3002