Literature DB >> 11641501

A trypanosome structure involved in transmitting cytoplasmic information during cell division.

F F Moreira-Leite1, T Sherwin, L Kohl, K Gull.   

Abstract

African trypanosomes are protozoan parasites that cause sleeping sickness in humans through a tsetse fly vector. The procyclic form of Trypanosoma brucei has a single, attached flagellum that describes a helical path along the cell from posterior to anterior. During division, a specific flagellum-flagellum connection is elaborated between the new and old flagellum. This connector was present only during cell duplication and was found to be involved in the replication of the helical cell pattern and polarity. This finding implicates the concept of cytotaxis in cell morphogenesis in trypanosomes.

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Year:  2001        PMID: 11641501     DOI: 10.1126/science.1063775

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  72 in total

Review 1.  Biology and mechanism of trypanosome cell motility.

Authors:  Kent L Hill
Journal:  Eukaryot Cell       Date:  2003-04

2.  Biochemical analysis of PIFTC3, the Trypanosoma brucei orthologue of nematode DYF-13, reveals interactions with established and putative intraflagellar transport components.

Authors:  Joseph B Franklin; Elisabetta Ullu
Journal:  Mol Microbiol       Date:  2010-10       Impact factor: 3.501

3.  Novel roles for the flagellum in cell morphogenesis and cytokinesis of trypanosomes.

Authors:  Linda Kohl; Derrick Robinson; Philippe Bastin
Journal:  EMBO J       Date:  2003-10-15       Impact factor: 11.598

4.  Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei.

Authors:  Sylvain Lacomble; Sue Vaughan; Catarina Gadelha; Mary K Morphew; Michael K Shaw; J Richard McIntosh; Keith Gull
Journal:  J Cell Sci       Date:  2010-08-03       Impact factor: 5.285

5.  Scanning and three-dimensional electron microscopy methods for the study of Trypanosoma brucei and Leishmania mexicana flagella.

Authors:  Eva Gluenz; Richard John Wheeler; Louise Hughes; Sue Vaughan
Journal:  Methods Cell Biol       Date:  2015-03-07       Impact factor: 1.441

6.  Pairwise knockdowns of cdc2-related kinases (CRKs) in Trypanosoma brucei identified the CRKs for G1/S and G2/M transitions and demonstrated distinctive cytokinetic regulations between two developmental stages of the organism.

Authors:  Xiaoming Tu; Ching C Wang
Journal:  Eukaryot Cell       Date:  2005-04

7.  An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei.

Authors:  Gareth W Morgan; Paul W Denny; Sue Vaughan; David Goulding; Tim R Jeffries; Deborah F Smith; Keith Gull; Mark C Field
Journal:  Mol Cell Biol       Date:  2005-05       Impact factor: 4.272

8.  Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes.

Authors:  Sabrina Absalon; Thierry Blisnick; Linda Kohl; Géraldine Toutirais; Gwénola Doré; Daria Julkowska; Arounie Tavenet; Philippe Bastin
Journal:  Mol Biol Cell       Date:  2007-12-19       Impact factor: 4.138

9.  Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa.

Authors:  Catarina Gadelha; Bill Wickstead; Wanderley de Souza; Keith Gull; Narcisa Cunha-e-Silva
Journal:  Eukaryot Cell       Date:  2005-03

Review 10.  Motility and more: the flagellum of Trypanosoma brucei.

Authors:  Gerasimos Langousis; Kent L Hill
Journal:  Nat Rev Microbiol       Date:  2014-07       Impact factor: 60.633

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