Literature DB >> 1164127

Metastatic adrenal cortical carcinoma. Documented cure with combined chemotherapy.

J A Ostuni, M S Roginsky.   

Abstract

In 1966, we published the case report of a patient with adrenal carcinoma and wide spread metatasis who, after treatment with mitotane (o,p-DDD) and fluorouracil, developed Addison disease accompanied by a clinical remission. The patient's unexpected death from an unrelated cause now allows us to verify what to our knowledge is the first cure of metastatic adrenal carcinoma by chemotherapy.

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Year:  1975        PMID： 1164127

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN： 0003-9926


  4 in total

1.  o,p'--DDD and adrenal carcinoma.

Authors:  P McKiernan; D A Doyle; G J Duffy; R P Towers; F A Duff; D K O'Donovan
Journal:  Ir J Med Sci       Date:  1978-12       Impact factor: 1.568

2.  Recurrent adrenal cortical carcinoma with Cushing's syndrome: twenty-five-year follow-up of a patient.

Authors:  M J Tikkanen; A Sivula; A Kahri; R Pelkonen
Journal:  J Endocrinol Invest       Date:  1980 Oct-Dec       Impact factor: 4.256

3.  O,p'-DDD (mitotane) levels in plasma and tissues during chemotherapy and at autopsy.

Authors:  H von Slooten; A P van Seters; D Smeenk; A J Moolenaar
Journal:  Cancer Chemother Pharmacol       Date:  1982       Impact factor: 3.333

4.  Feminizing adrenocortical carcinoma in man.

Authors:  M Nishiki; K Amano; H Itoh; H Ezaki; Y Miyachi
Journal:  Jpn J Surg       Date:  1980-06
  4 in total

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