Literature DB >> 1164100

[Effect of antihypertensive agents on the in vitro biosynthesis of prostaglandin E and F2 alpha in the rabbit kidney medulla].

H U Block, C Taube, W Föster.   

Abstract

This report describes the influence of antihypertensive drugs on the biosynthesis of prostaglandins from endogenous precursors in the homogenates of rabbit kidney medulla. Dihydralazine and reserpine inhibited, alpha-methyldopa on the contrary stimulated the in vitro biosynthesis of prostaglandins E and F2alpha. Clonidin was without effect. The effects of noradrenaline and indomethacine as standard substances were determined.

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Year:  1975        PMID： 1164100

Source DB:  PubMed          Journal:  Arch Int Pharmacodyn Ther        ISSN： 0003-9780


  2 in total

1.  Chemical sympathectomy abolishes the increase in blood pressure of linoleic acid deficient fed rats induced by salt loading.

Authors:  P Hoffmann; C Taube; K Pönicke; W Förster; L Somova; V Orbetzova; D Kiprov
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-08       Impact factor: 3.000

2.  Comparative study of the blood pressure effects of four different vegetable fats on young, spontaneously hypertensive rats.

Authors:  P Hoffmann; H U Block; J Beitz; C Taube; W Forster; P Wortha; P Singer; E Naumann; H Heine
Journal:  Lipids       Date:  1986-12       Impact factor: 1.880
  2 in total

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