Literature DB >> 116280

Effects of d-amphetamine, maprotiline, L-dopa, and haloperidol on the components of the predatory behavior of the ferret, Putorius furo L.

W J Schmidt.   

Abstract

Ferret predation on rats was examined in an arena. One hour before the test one of the following drugs was administered. d-Amphetamine (0.8 and 1.4 mg/kg IM), MAPROTILINE (10 AND 40 Mg/kg orally), L-dopa (30 and 60 mg/kg orally), or haloperidol (0.14 and 0.6 mg/kg IM). Provided that capture was successful, the sequence of the behavioral components was not changed by these drugs. With the exceptions of paw movements and rolling over, which were not affected by the drugs, the components of predatory behavior were influenced differently. This leads to the assumption that a drug affects different mechanisms which control behavior. It is assumed that dopamine is involved in the control of capture elicitation as well as in the control of pursuit and biting. Capture elicitation was inhibited by d-amphetamine and L-dopa, but not by maprotiline, and was even facilitated by haloperidol. The orientation of pursuit movements and biting was impaired by L-dopa and improved by haloperidol, whereas maprotiline did not influence these components.

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Year:  1979        PMID: 116280     DOI: 10.1007/bf00427524

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN: 0033-3158            Impact factor:   4.530


  18 in total

1.  Effects of imipramine, d-amphetamine, and tripelennamine on mouse and frog killing by the rat.

Authors:  G A Barr; K E Moyer; J L Gibbons
Journal:  Physiol Behav       Date:  1976-03

2.  Specific in vivo binding of neuroleptic drugs in rat brain.

Authors:  P Laduron; J Leysen
Journal:  Biochem Pharmacol       Date:  1977-05-15       Impact factor: 5.858

3.  Structural relationship and potency of agents which selectively block mouse killing (muricide) behavior in rats.

Authors:  R D Sofia
Journal:  Life Sci       Date:  1969-11-01       Impact factor: 5.037

4.  Some aspects of the mechanism of action of various stimulant amphetamine analogues.

Authors:  J Scheel-Krüger
Journal:  Psychiatr Neurol Neurochir       Date:  1972 May-Jun

5.  Effects of drugs on the mouse-killing (muricide) test and its relationship to amygdaloid function.

Authors:  Z P Horovitz; J J Piala; J P High; J C Burke; R C Leaf
Journal:  Int J Neuropharmacol       Date:  1966-11

6.  Initiation of mouse killing in non-killer rats by repeated pilocarpine treatment.

Authors:  J R Vogel; R C Leaf
Journal:  Physiol Behav       Date:  1972-03

7.  Evidence for inhibition by brain serotonin of mouse killing behaviour in rats.

Authors:  G Di Chiara; R Camba; P F Spano
Journal:  Nature       Date:  1971-09-24       Impact factor: 49.962

8.  Chlorimipramine inhibition of muricide: the role of the ascending 5-HT projection.

Authors:  P C Marks; M O'Brien; G Paxinos
Journal:  Brain Res       Date:  1978-06-23       Impact factor: 3.252

9.  Noradrenaline synthesis from L-DOPA in rodents and its relationship to motor activity.

Authors:  A Dolphin; P Jenner; C D Marsden
Journal:  Pharmacol Biochem Behav       Date:  1976-10       Impact factor: 3.533

10.  Para-chlorophenylalanine, serotonin and killing behavior.

Authors:  K A Miczek; J L Altman; J B Appel; W O Boggan
Journal:  Pharmacol Biochem Behav       Date:  1975 May-Jun       Impact factor: 3.533

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  3 in total

1.  Unlike rats, ferrets do kill under antidepressants.

Authors:  W J Schmidt
Journal:  Naturwissenschaften       Date:  1980-05

2.  Facilitatory effect of ventral tegmental area A10 region on the attack behaviour in the cat: possible dopaminergic role in selective attention.

Authors:  P V Piazza; M Ferdico; D Russo; G Crescimanno; A Benigno; G Amato
Journal:  Exp Brain Res       Date:  1988       Impact factor: 1.972

3.  Involvement of dopaminergic neurotransmission in the control of goal-directed movements.

Authors:  W J Schmidt
Journal:  Psychopharmacology (Berl)       Date:  1983       Impact factor: 4.530

  3 in total

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