Metastatic subcutaneous zygomycosis following intravenous and intracerebral inoculation of Absidia corymbifera spores.

A subcutaneous granuloma developed in a C3H mouse ca. 5 months after sequential intravenous and intracerebral inoculation of Absidia corymbifera spores. A. corymbifera was demonstrated microscopically and culturally in the lesion. Infection is believed to have been secondary to fungal infection of the kidney. The histopathological features of the lesion are described.