Literature DB >> 11624293

Camillo Golgi's scientific biography.

P Mazzarello1.   

Abstract

Born in Corteno, a tiny village in the province of Brescia, Camillo Golgi studied at the University of Pavia where he graduated in medicine in 1865 under the guidance of the psychiatrist Cesare Lombroso who sparked his vocation to study the brain. Golgi then began to learn histological techniques under the direction of the pathologist Giulio Bizzozero. In 1872 he moved to Abbiategrasso as chief of a hospital for chronic diseases. In a rudimentary laboratory he developed the silver-bichromate staining technique, the 'black reaction', which was a breakthrough for nervous tissue structure research. While in Abbiategrasso Golgi demonstrated the branching of the axons, and observed striatal and cortical lesions in a case of chorea. He returned to Pavia as Professor of Histology and General Pathology, and made a series of important discoveries that still bear his name: the Golgi tendon organ, the Golgi-Mazzoni corpuscles, another Golgi method to stain nerve cells based on the use of potassium dichromate and mercuric chloride, the canaliculi of the parietal cells of the gastric glands (Muller-Golgi tubules), the Golgi-Rezzonico myelin's annular apparatus (or Golgi-Rezzonico horny funnels), the cycle of malarian parasites (Golgi cycle), the relationship between recurrent malarian fever bouts and the multiplication of the Plasmodium in the blood (Golgi law), the relationship between the vascular pole of the Malpighian glomerulus and the distal tubule, the Golgi's pericellular nets and finally, and most importantly, the cytoplasmic 'internal reticular apparatus' (Golgi apparatus). In 1906 Golgi was awarded the Nobel prize for Medicine or Physiology. He died in Pavia on 21 January 1921.

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Mesh:

Year:  1999        PMID: 11624293     DOI: 10.1076/jhin.8.2.121.1836

Source DB:  PubMed          Journal:  J Hist Neurosci        ISSN: 0964-704X            Impact factor:   0.529


  3 in total

1.  A modified method for consistent and reliable Golgi-cox staining in significantly reduced time.

Authors:  Amit Ranjan; Birendra Nath Mallick
Journal:  Front Neurol       Date:  2010-12-28       Impact factor: 4.003

Review 2.  The Physiology of the Gastric Parietal Cell.

Authors:  Amy C Engevik; Izumi Kaji; James R Goldenring
Journal:  Physiol Rev       Date:  2019-10-31       Impact factor: 37.312

Review 3.  Camillo Golgi (1843-1926): scientist extraordinaire and pioneer figure of modern neurology.

Authors:  Sanjib Kumar Ghosh
Journal:  Anat Cell Biol       Date:  2020-12-31
  3 in total

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