Literature DB >> 11606948

Regulation of lipid and lipoprotein metabolism by retinoids.

B Staels1.   

Abstract

Retinoids are small vitamin A-derived lipophilic compounds that influence a wide variety of developmental and metabolic processes. Retinoids exert their action by activating transcription factors belonging to the retinoic acid receptor (RAR) and retinoid X receptor (RXR) subfamilies of nuclear receptors. Therapeutically, retinoids are used for the treatment of dermatological disorders and certain cancers. Dyslipidemia is a common side-effect of therapy with the currently available retinoids. This review summarizes our current understanding of the molecular mechanisms of regulation of lipid and lipoprotein metabolism by retinoids.

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Year:  2001        PMID: 11606948     DOI: 10.1067/mjd.2001.113718

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  27 in total

1.  HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues.

Authors:  Maureen A Kane; Alexandra E Folias; Joseph L Napoli
Journal:  Anal Biochem       Date:  2008-03-25       Impact factor: 3.365

2.  All-Trans-Retinoic Acid Enhances Mitochondrial Function in Models of Human Liver.

Authors:  Sasmita Tripathy; John D Chapman; Chang Y Han; Cathryn A Hogarth; Samuel L M Arnold; Jennifer Onken; Travis Kent; David R Goodlett; Nina Isoherranen
Journal:  Mol Pharmacol       Date:  2016-02-26       Impact factor: 4.436

3.  Sulindac-derived retinoid X receptor-α modulator attenuates atherosclerotic plaque progression and destabilization in ApoE-/- mice.

Authors:  Linghong Shen; Zhe Sun; Peng Nie; Ruosen Yuan; Zhaohua Cai; Caizhe Wu; Liuhua Hu; Shuxuan Jin; Hu Zhou; Xiaokun Zhang; Ben He
Journal:  Br J Pharmacol       Date:  2019-05-23       Impact factor: 8.739

4.  Genome-wide profiling of liver X receptor, retinoid X receptor, and peroxisome proliferator-activated receptor α in mouse liver reveals extensive sharing of binding sites.

Authors:  Michael Boergesen; Thomas Åskov Pedersen; Barbara Gross; Simon J van Heeringen; Dik Hagenbeek; Christian Bindesbøll; Sandrine Caron; Fanny Lalloyer; Knut R Steffensen; Hilde I Nebb; Jan-Åke Gustafsson; Hendrik G Stunnenberg; Bart Staels; Susanne Mandrup
Journal:  Mol Cell Biol       Date:  2011-12-12       Impact factor: 4.272

5.  Pro- and anti-inflammatory adipokines are associated with cardiometabolic risk markers in Brazilian schoolchildren.

Authors:  Mariana De Santis Filgueiras; Milene Cristine Pessoa; Josefina Bressan; Fernanda Martins de Albuquerque; Lara Gomes Suhett; Mariane Alves Silva; Juliana Farias de Novaes
Journal:  Eur J Pediatr       Date:  2021-04-09       Impact factor: 3.183

Review 6.  Familial dyslipidaemias: an overview of genetics, pathophysiology and management.

Authors:  Sahar B Hachem; Arshag D Mooradian
Journal:  Drugs       Date:  2006       Impact factor: 9.546

7.  Quantification of endogenous retinoids.

Authors:  Maureen A Kane; Joseph L Napoli
Journal:  Methods Mol Biol       Date:  2010

Review 8.  Guidelines for the management of acne vulgaris in adolescents.

Authors:  Victoria Goulden
Journal:  Paediatr Drugs       Date:  2003       Impact factor: 3.022

9.  Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver.

Authors:  Fanny Lalloyer; Thomas Askov Pedersen; Barbara Gross; Sophie Lestavel; Saïd Yous; Emmanuelle Vallez; Jan-Ake Gustafsson; Susanne Mandrup; Catherine Fiévet; Bart Staels; Anne Tailleux
Journal:  Arterioscler Thromb Vasc Biol       Date:  2009-07-10       Impact factor: 8.311

10.  Quantitative profiling of endogenous retinoic acid in vivo and in vitro by tandem mass spectrometry.

Authors:  Maureen A Kane; Alexandra E Folias; Chao Wang; Joseph L Napoli
Journal:  Anal Chem       Date:  2008-02-06       Impact factor: 6.986

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