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Literature DB >> 11604319

Transgenic plants as protein factories.

Abstract

Transgenic plants are showing considerable potential for the economic production of proteins, with a few already being marketed. Recent clinical trials of pharmaceuticals produced from transgenic plants are encouraging, with plant glycans showing reassuringly poor immunogenicity. Our increasing understanding of protein targeting and accumulation should further improve the potential of this new technology.

Entities: Chemical

Mesh：

Substances：

Year: 2001 PMID： 11604319 DOI： 10.1016/s0958-1669(00)00244-5

Source DB: PubMed Journal: Curr Opin Biotechnol ISSN： 0958-1669 Impact factor: 9.740

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Cited

28 in total

1. Inducible expression in plants by virus-mediated transgene activation.

Authors: Anna K Hull; Vidadi Yusibov; Vadim Mett
Journal: Transgenic Res Date: 2005-08 Impact factor: 2.788

2. Expression of cholera toxin B subunit in transgenic rice endosperm.

Authors: Maria Oszvald; Tae-Jin Kang; Sandor Tomoskozi; Barnabas Jenes; Tae-Geum Kim; Youn-Soo Cha; Laszlo Tamas; Moon-Sik Yang
Journal: Mol Biotechnol Date: 2008-07-10 Impact factor: 2.695

3. Plant derived veterinary vaccines.

Authors: L Santi
Journal: Vet Res Commun Date: 2009-09 Impact factor: 2.459

4. Engineering and expression of a RhoA peptide against respiratory syncytial virus infection in plants.

Authors: Benita Ortega-Berlanga; Konstantin Musiychuk; Yoko Shoji; Jessica A Chichester; Vidadi Yusibov; Omar Patiño-Rodríguez; Daniel E Noyola; Ángel G Alpuche-Solís
Journal: Planta Date: 2015-10-16 Impact factor: 4.116

Review 5. Expression of recombinant vaccines and antibodies in plants.

Authors: Kisung Ko
Journal: Monoclon Antib Immunodiagn Immunother Date: 2014-06

6. A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses.

Authors: Hidenori Takagi; Takachika Hiroi; Lijun Yang; Yoshifumi Tada; Yoshikazu Yuki; Kaoru Takamura; Ryotaro Ishimitsu; Hideyuki Kawauchi; Hiroshi Kiyono; Fumio Takaiwa
Journal: Proc Natl Acad Sci U S A Date: 2005-11-08 Impact factor: 11.205

Transgenic plants as protein factories.

1. Inducible expression in plants by virus-mediated transgene activation.

2. Expression of cholera toxin B subunit in transgenic rice endosperm.

3. Plant derived veterinary vaccines.

4. Engineering and expression of a RhoA peptide against respiratory syncytial virus infection in plants.

Review 5. Expression of recombinant vaccines and antibodies in plants.

6. A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses.

7. Expression of a staphylokinase, a thrombolytic agent in Arabidopsis thaliana.

8. Improved in planta expression of the human islet autoantigen glutamic acid decarboxylase (GAD65).

Review 9. Plant-based oral vaccines: results of human trials.

10. Stable-isotope labeling using an inducible viral infection system in suspension-cultured plant cells.