Literature DB >> 11603281

Salvia miltiorrhiza and ischemic diseases.

X Y Ji1, B K Tan, Y Z Zhu.   

Abstract

The demonstration of beneficial effects of salvia miltiorrhiza (DanShen) on ischemic diseases has revolutionized the management of angina pectoris, myocardial infarction (MI) or stroke in Chinese society. Experimental studies have shown that DanShen dilated coronary arteries, increased coronary blood flow, and scavenged free radicals in ischemic diseases, so that it reduced the cellular damage from ischemia and improved heart functions. Clinical trials also indicated that DanShen was an effective medicine for angina pectoris, MI, and stroke. This review will focus on DanShen's effects in angina pectoris, MI and stroke.

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Year:  2000        PMID： 11603281

Source DB:  PubMed          Journal:  Acta Pharmacol Sin        ISSN： 1671-4083            Impact factor:   6.150


  62 in total

1.  Magnesium lithospermate B extracted from Salvia miltiorrhiza elevates intracellular Ca(2+) level in SH-SY5Y cells.

Authors:  Yi-Ching Chen; Tzyy-Rong Jinn; Tse-Yu Chung; Feng-Yin Li; Ruey-Jane Fan; Jason Tc Tzen
Journal:  Acta Pharmacol Sin       Date:  2010-08       Impact factor: 6.150

Review 2.  Therapeutic effects of traditional herbal medicine on cerebral ischemia: a perspective of vascular protection.

Authors:  Youngmin Bu; Kyungjin Lee; Hyuk-Sang Jung; Sang-Kwan Moon
Journal:  Chin J Integr Med       Date:  2013-10-30       Impact factor: 1.978

Review 3.  Molecular evidence of cryptotanshinone for treatment and prevention of human cancer.

Authors:  Wenxing Chen; Yin Lu; Guangying Chen; Shile Huang
Journal:  Anticancer Agents Med Chem       Date:  2013-09       Impact factor: 2.505

4.  Protocatechuic aldehyde protects against isoproterenol-induced cardiac hypertrophy via inhibition of the JAK2/STAT3 signaling pathway.

Authors:  Xiuli Fang; Yajun Liu; Jing Lu; Huiqi Hong; Jing Yuan; Yuhong Zhang; Panxia Wang; Peiqing Liu; Jiantao Ye
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2018-08-21       Impact factor: 3.000

5.  Preparation of przewalskinic acid A from salvianolic acid B using a crude enzyme from an Aspergillus oryzae strain.

Authors:  Chunying Liu; Yinghua Jin; Hongshan Yu; Changkai Sun; Shuiping Zhou; Yonghong Zhu; Longquan Xu; Chong Yu; Fengxie Jin
Journal:  J Ind Microbiol Biotechnol       Date:  2014-03-11       Impact factor: 3.346

Review 6.  Targeting HMGB1 in the treatment of sepsis.

Authors:  Haichao Wang; Mary F Ward; Andrew E Sama
Journal:  Expert Opin Ther Targets       Date:  2014-01-06       Impact factor: 6.902

7.  Caging a Beast in the Inflammation Arena: Use of Chinese Medicinal Herbs to Inhibit a Late Mediator of Lethal Sepsis, HMGB1.

Authors:  Shu Zhu; Wei Li; Jianhua Li; Andrew E Sama; Haichao Wang
Journal:  Int J Clin Exp Med       Date:  2008-01-20

Review 8.  High mobility group box 1 protein as a potential drug target for infection- and injury-elicited inflammation.

Authors:  Shu Zhu; Wei Li; Mary F Ward; Andrew E Sama; Haichao Wang
Journal:  Inflamm Allergy Drug Targets       Date:  2010-03

9.  Effect of Danshen aqueous extract on serum hs-CRP, IL-8, IL-10, TNF-α levels, and IL-10 mRNA, TNF-α mRNA expression levels, cerebral TGF-β1 positive expression level and its neuroprotective mechanisms in CIR rats.

Authors:  Xue-Yun Liang; Hai-Ning Li; Xiao-Yan Yang; Wen-Yan Zhou; Jian-Guo Niu; Ben-Dong Chen
Journal:  Mol Biol Rep       Date:  2013-02-02       Impact factor: 2.316

10.  Effect of danshen extract on pharmacokinetics of theophylline in healthy volunteers.

Authors:  Furong Qiu; Guangji Wang; Yanan Zhao; Hua Sun; Guoguang Mao; Jiyi A; Jian Sun
Journal:  Br J Clin Pharmacol       Date:  2007-10-24       Impact factor: 4.335
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