Literature DB >> 11601733

Blood flow in abdominal aortic aneurysms: pulsatile flow hemodynamics.

E A Finol1, C H Amon.   

Abstract

Numerical predictions of blood flow patterns and hemodynamic stresses in Abdominal Aortic Aneurysms (AAAs) are performed in a two-aneurysm, axisymmetric, rigid wall model using the spectral element method. Physiologically realistic aortic blood flow is simulated under pulsatile conditions for the range of time-averaged Reynolds numbers 50< or =Re(m)< or =300, corresponding to a range of peak Reynolds numbers 262.5< or =Re(peak) < or = 1575. The vortex dynamics induced by pulsatile flow in AAAs is characterized by a sequence of five different flow phases in one period of the flow cycle. Hemodynamic disturbance is evaluated for a modified set of indicator functions, which include wall pressure (p(w)), wall shear stress (tau(w)), and Wall Shear Stress Gradient (WSSG). At peak flow, the highest shear stress and WSSG levels are obtained downstream of both aneurysms, in a pattern similar to that of steady flow. Maximum values of wall shear stresses and wall shear stress gradients obtained at peak flow are evaluated as a function of the time-average Reynolds number resulting in a fourth order polynomial correlation. A comparison between predictions for steady and pulsatile flow is presented, illustrating the importance of considering time-dependent flow for the evaluation of hemodynamic indicators.

Entities:  

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Year:  2001        PMID: 11601733     DOI: 10.1115/1.1395573

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  11 in total

1.  Arterial geometry, flow pattern, wall shear and mass transport: potential physiological significance.

Authors:  G Coppola; C Caro
Journal:  J R Soc Interface       Date:  2008-11-25       Impact factor: 4.118

2.  A Distributed Lumped Parameter Model of Blood Flow.

Authors:  Mehran Mirramezani; Shawn C Shadden
Journal:  Ann Biomed Eng       Date:  2020-07-01       Impact factor: 3.934

3.  Effects of intraluminal thrombus on patient-specific abdominal aortic aneurysm hemodynamics via stereoscopic particle image velocity and computational fluid dynamics modeling.

Authors:  Chia-Yuan Chen; Raúl Antón; Ming-yang Hung; Prahlad Menon; Ender A Finol; Kerem Pekkan
Journal:  J Biomech Eng       Date:  2014-03       Impact factor: 2.097

4.  Recent advances in the application of computational mechanics to the diagnosis and treatment of cardiovascular disease.

Authors:  Juan C Del Alamo; Alison L Marsden; Juan C Lasheras
Journal:  Rev Esp Cardiol       Date:  2009-07       Impact factor: 4.753

Review 5.  Intracranial and abdominal aortic aneurysms: similarities, differences, and need for a new class of computational models.

Authors:  J D Humphrey; C A Taylor
Journal:  Annu Rev Biomed Eng       Date:  2008       Impact factor: 9.590

6.  Blood flow and coherent vortices in the normal and aneurysmatic aortas: a fluid dynamical approach to intra-luminal thrombus formation.

Authors:  Jacopo Biasetti; Fazle Hussain; T Christian Gasser
Journal:  J R Soc Interface       Date:  2011-04-06       Impact factor: 4.118

7.  Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening.

Authors:  John F LaDisa; Lars E Olson; Douglas A Hettrick; David C Warltier; Judy R Kersten; Paul S Pagel
Journal:  Biomed Eng Online       Date:  2005-10-26       Impact factor: 2.819

8.  Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling.

Authors:  John F LaDisa; Lars E Olson; Hettrick A Douglas; David C Warltier; Judy R Kersten; Paul S Pagel
Journal:  Biomed Eng Online       Date:  2006-06-16       Impact factor: 2.819

9.  Characteristics of pulsatile flows in curved stenosed channels.

Authors:  Hyeonji Hong; Eunseop Yeom; Ho Seong Ji; Hyun Dong Kim; Kyung Chun Kim
Journal:  PLoS One       Date:  2017-10-19       Impact factor: 3.240

10.  Vascular Deformation Mapping of Abdominal Aortic Aneurysm.

Authors:  Drew J Braet; Jonathan Eliason; Yunus Ahmed; Pieter A J van Bakel; Jiayang Zhong; Zhangxing Bian; Carlos Alberto Figueroa; Nicholas S Burris
Journal:  Tomography       Date:  2021-05-13
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