Literature DB >> 1159813

Adriamycin-induced cardiac damage in the mouse: a small-animal model of cardiotoxicity.

S H Rosenoff, H M Olson, D M Young, F Bostick, R C Young.   

Abstract

After one dose of adriamycin, a subacute cardiomyopathy was observed in the mouse by both light and electron microscopy. The microscopic alterations were characterized by single-cell necrosis and mitochondrial degeneration. These lesions were similar to those seen in man and shortly preceded fatal toxicity.

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Year:  1975        PMID: 1159813     DOI: 10.1093/jnci/55.1.191

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN: 0027-8874            Impact factor:   13.506


  19 in total

Review 1.  Doxorubicin effects on contractile structures and molecules.

Authors:  R Colombo; A Milzani; A Necco; G Vailati
Journal:  Cytotechnology       Date:  1990-01       Impact factor: 2.058

2.  Redox proteomic identification of HNE-bound mitochondrial proteins in cardiac tissues reveals a systemic effect on energy metabolism after doxorubicin treatment.

Authors:  Y Zhao; S Miriyala; L Miao; M Mitov; D Schnell; S K Dhar; J Cai; J B Klein; R Sultana; D A Butterfield; M Vore; I Batinic-Haberle; S Bondada; D K St Clair
Journal:  Free Radic Biol Med       Date:  2014-03-12       Impact factor: 7.376

3.  The role of calcium in the toxicity of the myocardium.

Authors:  M Borgers
Journal:  Histochem J       Date:  1981-09

4.  Evaluation of antitumor drug side effects in small animals.

Authors:  W T Bradner; J E Schurig; J B Huftalen; G J Doyle
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

5.  Elevation of serum lipid peroxide level associated with doxorubicin toxicity and its amelioration by [dl]-alpha-tocopheryl acetate or coenzyme Q10 in mouse (doxorubicin, toxicity, lipid peroxide, tocopherol, coenzyme Q10).

Authors:  N Yamanaka; T Kato; K Nishida; T Fujikawa; M Fukushima; K Ota
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

6.  Effect of amrinone on anthracycline-induced lethal and cardiac toxicity in mice and rats.

Authors:  F Villani; C Manzotti; M Mella; E Monti; G Savi; F Zunino
Journal:  Med Oncol Tumor Pharmacother       Date:  1990

7.  Similar changes in cardiac morphology and DNA synthesis induced by doxorubicin and 4'-epi-doxorubicin.

Authors:  K Wassermann; K Mølgaard; E Steiness
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

8.  Evaluation of free radical effects and catecholamine alterations in adriamycin cardiotoxicity.

Authors:  J A Jackson; J P Reeves; K H Muntz; D Kruk; R A Prough; J T Willerson; L M Buja
Journal:  Am J Pathol       Date:  1984-10       Impact factor: 4.307

9.  Prevention of doxorubicin-induced myocardial and haematological toxicities in rats by the iron chelator desferrioxamine.

Authors:  M M al-Harbi; N M al-Gharably; O A al-Shabanah; A M al-Bekairi; A M Osman; H N Tawfik
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

10.  Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury.

Authors:  Chotiros Daosukho; Yumin Chen; Teresa Noel; Pradoldej Sompol; Ramaneeya Nithipongvanitch; Joyce M Velez; Terry D Oberley; Daret K St Clair
Journal:  Free Radic Biol Med       Date:  2007-03-12       Impact factor: 7.376

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