Literature DB >> 11598099

Mycobacterium ulcerans cytotoxicity in an adipose cell model.

K M Dobos1, P L Small, M Deslauriers, F D Quinn, C H King.   

Abstract

An adipose cell (SW872) model was developed to observe cellular necrosis and apoptosis upon Mycobacterium ulcerans infection and treatment with mycobacterial exudate. Apoptosis was likely due to secreted proteins, while necrosis was likely due to mycolactone. Our data suggest that additional factors in M. ulcerans may be involved in Buruli ulcer pathogenesis.

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Year:  2001        PMID: 11598099      PMCID: PMC100123          DOI: 10.1128/IAI.69.11.7182-7186.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  19 in total

1.  Comparison of in vitro models for the study of Mycobacterium tuberculosis invasion and intracellular replication.

Authors:  P K Mehta; C H King; E H White; J J Murtagh; F D Quinn
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

2.  The primary isolation of mycobacterium ulcerans.

Authors:  A Y Tsang; E R Farber
Journal:  Am J Clin Pathol       Date:  1973-05       Impact factor: 2.493

3.  Immunosuppressive properties of the soluble toxin from Mycobacterium ulcerans.

Authors:  M Pimsler; T A Sponsler; W M Meyers
Journal:  J Infect Dis       Date:  1988-03       Impact factor: 5.226

Review 4.  Out of Africa: observations on the histopathology of Mycobacterium ulcerans infection.

Authors:  J Hayman
Journal:  J Clin Pathol       Date:  1993-01       Impact factor: 3.411

5.  Further characterization of Mycobacterium ulcerans toxin.

Authors:  W T Hockmeyer; R E Krieg; M Reich; R D Johnson
Journal:  Infect Immun       Date:  1978-07       Impact factor: 3.441

6.  Partial purification and characterization of biological effects of a lipid toxin produced by Mycobacterium ulcerans.

Authors:  K M George; L P Barker; D M Welty; P L Small
Journal:  Infect Immun       Date:  1998-02       Impact factor: 3.441

7.  Definition of Mycobacterium tuberculosis culture filtrate proteins by two-dimensional polyacrylamide gel electrophoresis, N-terminal amino acid sequencing, and electrospray mass spectrometry.

Authors:  M G Sonnenberg; J T Belisle
Journal:  Infect Immun       Date:  1997-11       Impact factor: 3.441

8.  Detection of phospholipase C in nontuberculous mycobacteria and its possible role in hemolytic activity.

Authors:  A Gomez; A Mve-Obiang; B Vray; W Rudnicka; I C Shamputa; F Portaels; W M Meyers; P A Fonteyne; L Realini
Journal:  J Clin Microbiol       Date:  2001-04       Impact factor: 5.948

9.  Mycobacterium marinum persists in cultured mammalian cells in a temperature-restricted fashion.

Authors:  L Ramakrishnan; S Falkow
Journal:  Infect Immun       Date:  1994-08       Impact factor: 3.441

10.  Intracellular growth and cytotoxicity of Mycobacterium haemophilum in a human epithelial cell line (Hec-1-B).

Authors:  L J Fischer; F D Quinn; E H White; C H King
Journal:  Infect Immun       Date:  1996-01       Impact factor: 3.441

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  20 in total

1.  Total Synthesis of Mycolactones A and B.

Authors:  Fengbin Song; Steve Fidanze; Andrew B Benowitz; Yoshito Kishi
Journal:  Tetrahedron       Date:  2007-06-25       Impact factor: 2.457

2.  Use of the immunodominant 18-kiloDalton small heat shock protein as a serological marker for exposure to Mycobacterium ulcerans.

Authors:  Diana Diaz; Heinz Döbeli; Dorothy Yeboah-Manu; Ernestina Mensah-Quainoo; Arno Friedlein; Nicole Soder; Simona Rondini; Thomas Bodmer; Gerd Pluschke
Journal:  Clin Vaccine Immunol       Date:  2006-10-04

Review 3.  Buruli Ulcer, a Prototype for Ecosystem-Related Infection, Caused by Mycobacterium ulcerans.

Authors:  Dezemon Zingue; Amar Bouam; Roger B D Tian; Michel Drancourt
Journal:  Clin Microbiol Rev       Date:  2017-12-13       Impact factor: 26.132

Review 4.  The chemistry and biology of mycolactones.

Authors:  Matthias Gehringer; Karl-Heinz Altmann
Journal:  Beilstein J Org Chem       Date:  2017-08-11       Impact factor: 2.883

5.  Aquatic insects as a vector for Mycobacterium ulcerans.

Authors:  Laurent Marsollier; Raymond Robert; Jacques Aubry; Jean-Paul Saint André; Henri Kouakou; Pierre Legras; Anne-Lise Manceau; Chetaou Mahaza; Bernard Carbonnelle
Journal:  Appl Environ Microbiol       Date:  2002-09       Impact factor: 4.792

6.  Antioxidants protect keratinocytes against M. ulcerans mycolactone cytotoxicity.

Authors:  Alvar Grönberg; Louise Zettergren; Kerstin Bergh; Mona Ståhle; Johan Heilborn; Kristian Angeby; Pamela L Small; Hannah Akuffo; Sven Britton
Journal:  PLoS One       Date:  2010-11-04       Impact factor: 3.240

7.  Mycolactone is responsible for the painlessness of Mycobacterium ulcerans infection (buruli ulcer) in a murine study.

Authors:  Junichiro En; Masamichi Goto; Kazue Nakanaga; Michiyo Higashi; Norihisa Ishii; Hajime Saito; Suguru Yonezawa; Hirofumi Hamada; Pamela L C Small
Journal:  Infect Immun       Date:  2008-03-03       Impact factor: 3.441

8.  Development and application of real-time PCR assay for quantification of Mycobacterium ulcerans DNA.

Authors:  S Rondini; E Mensah-Quainoo; H Troll; T Bodmer; G Pluschke
Journal:  J Clin Microbiol       Date:  2003-09       Impact factor: 5.948

9.  Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans.

Authors:  Nicole Scherr; Philipp Gersbach; Jean-Pierre Dangy; Claudio Bomio; Jun Li; Karl-Heinz Altmann; Gerd Pluschke
Journal:  PLoS Negl Trop Dis       Date:  2013-03-28

10.  Histopathologic features of Mycobacterium ulcerans infection.

Authors:  Jeannette Guarner; Jeanine Bartlett; Ellen A Spotts Whitney; Pratima L Raghunathan; Ymkje Stienstra; Kwame Asamoa; Samuel Etuaful; Erasmus Klutse; Eric Quarshie; Tjip S van der Werf; Winette T A van der Graaf; C Harold King; David A Ashford
Journal:  Emerg Infect Dis       Date:  2003-06       Impact factor: 6.883

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