Literature DB >> 11598094

Resistance of T-cell receptor delta-chain-deficient mice to experimental Candida albicans vaginitis.

F L Wormley1, C Steele, K Wozniak, K Fujihashi, J R McGhee, P L Fidel.   

Abstract

Conditions consistent with tolerance or immunoregulation have been observed in experimental Candida albicans vaginal infections. The present study investigated the role of gamma/delta T cells in experimental vaginal candidiasis. Results showed that T-cell receptor delta-chain-knockout mice had significantly less vaginal fungal burden when compared to wild-type mice, suggesting an immunoregulatory role for gamma/delta T cells in Candida vaginitis.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11598094      PMCID: PMC100112          DOI: 10.1128/IAI.69.11.7162-7164.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  21 in total

1.  Local Th1/Th2 cytokine production during experimental vaginal candidiasis: potential importance of transforming growth factor-beta.

Authors:  B N Taylor; M Saavedra; P L Fidel
Journal:  Med Mycol       Date:  2000-12       Impact factor: 4.076

2.  Phenotypic analysis and gamma delta-T cell receptor repertoire of murine T cells associated with the vaginal epithelium.

Authors:  D Nandi; J P Allison
Journal:  J Immunol       Date:  1991-09-15       Impact factor: 5.422

3.  Growth inhibition of Candida albicans by vaginal cells from naïve mice.

Authors:  C Steele; H Ozenci; W Luo; M Scott; P L Fidel
Journal:  Med Mycol       Date:  1999-08       Impact factor: 4.076

Review 4.  Pathogenesis and treatment of recurrent vulvovaginal candidiasis.

Authors:  J D Sobel
Journal:  Clin Infect Dis       Date:  1992-03       Impact factor: 9.079

5.  Homing of a gamma delta thymocyte subset with homogeneous T-cell receptors to mucosal epithelia.

Authors:  S Itohara; A G Farr; J J Lafaille; M Bonneville; Y Takagaki; W Haas; S Tonegawa
Journal:  Nature       Date:  1990-02-22       Impact factor: 49.962

6.  Gamma delta-T cells are critical for survival and early proinflammatory cytokine gene expression during murine Klebsiella pneumonia.

Authors:  T A Moore; B B Moore; M W Newstead; T J Standiford
Journal:  J Immunol       Date:  2000-09-01       Impact factor: 5.422

7.  Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen.

Authors:  P Mombaerts; J Arnoldi; F Russ; S Tonegawa; S H Kaufmann
Journal:  Nature       Date:  1993-09-02       Impact factor: 49.962

8.  Candida-specific cell-mediated immunity is demonstrable in mice with experimental vaginal candidiasis.

Authors:  P L Fidel; M E Lynch; J D Sobel
Journal:  Infect Immun       Date:  1993-05       Impact factor: 3.441

9.  T cell receptor delta gene mutant mice: independent generation of alpha beta T cells and programmed rearrangements of gamma delta TCR genes.

Authors:  S Itohara; P Mombaerts; J Lafaille; J Iacomini; A Nelson; A R Clarke; M L Hooper; A Farr; S Tonegawa
Journal:  Cell       Date:  1993-02-12       Impact factor: 41.582

10.  Effects of preinduced Candida-specific systemic cell-mediated immunity on experimental vaginal candidiasis.

Authors:  P L Fidel; M E Lynch; J D Sobel
Journal:  Infect Immun       Date:  1994-03       Impact factor: 3.441

View more
  16 in total

1.  Respective IL-17A production by γδ T and Th17 cells and its implication in host defense against chlamydial lung infection.

Authors:  Hong Bai; Xiaoling Gao; Lei Zhao; Ying Peng; Jie Yang; Sai Qiao; Huili Zhao; Shuhe Wang; YiJun Fan; Antony George Joyee; Zhi Yao; Xi Yang
Journal:  Cell Mol Immunol       Date:  2016-10-31       Impact factor: 11.530

Review 2.  Cytokines in the host response to Candida vaginitis: Identifying a role for non-classical immune mediators, S100 alarmins.

Authors:  Junko Yano; Mairi C Noverr; Paul L Fidel
Journal:  Cytokine       Date:  2011-12-17       Impact factor: 3.861

3.  Role for dendritic cells in immunoregulation during experimental vaginal candidiasis.

Authors:  Dana M LeBlanc; Melissa M Barousse; Paul L Fidel
Journal:  Infect Immun       Date:  2006-06       Impact factor: 3.441

4.  Prospects for development of a vaccine to prevent and control vaginal candidiasis.

Authors:  Paul L Fidel; Jim E Cutler
Journal:  Curr Infect Dis Rep       Date:  2011-02       Impact factor: 3.725

5.  An intravaginal live Candida challenge in humans leads to new hypotheses for the immunopathogenesis of vulvovaginal candidiasis.

Authors:  Paul L Fidel; Melissa Barousse; Terri Espinosa; Mercedes Ficarra; Joy Sturtevant; David H Martin; Alison J Quayle; Kathleen Dunlap
Journal:  Infect Immun       Date:  2004-05       Impact factor: 3.441

6.  Immune cell-mediated protection against vaginal candidiasis: evidence for a major role of vaginal CD4(+) T cells and possible participation of other local lymphocyte effectors.

Authors:  Giorgio Santoni; Maria Boccanera; Daniela Adriani; Roberta Lucciarini; Consuelo Amantini; Stefania Morrone; Antonio Cassone; Flavia De Bernardis
Journal:  Infect Immun       Date:  2002-09       Impact factor: 3.441

7.  Immune Regulation and Its Role in the Pathogenesis of Candida Vaginitis.

Authors:  Paul L. Fidel
Journal:  Curr Infect Dis Rep       Date:  2003-12       Impact factor: 3.725

Review 8.  Novel Mechanism behind the Immunopathogenesis of Vulvovaginal Candidiasis: "Neutrophil Anergy".

Authors:  Junko Yano; Brian M Peters; Mairi C Noverr; Paul L Fidel
Journal:  Infect Immun       Date:  2018-02-20       Impact factor: 3.441

9.  Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia.

Authors:  Ping Cheng; Tao Liu; Wei-Ying Zhou; Yuan Zhuang; Liu-sheng Peng; Jin-Yu Zhang; Zhi-Nan Yin; Xu-hu Mao; Gang Guo; Yun Shi; Quan-ming Zou
Journal:  BMC Immunol       Date:  2012-07-09       Impact factor: 3.615

Review 10.  Candidiasis--do we need to fight or to tolerate the Candida fungus?

Authors:  M Raska; J Bĕláková; M Krupka; E Weigl
Journal:  Folia Microbiol (Praha)       Date:  2007       Impact factor: 2.629

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.