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Literature DB >> 11598020

Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.

Abstract

During S phase, chromatid cohesion is established only between nascent sisters and with faithful pairing along their entire region, but how this is ensured is unknown. Here we report that sister chromatid cohesion is formed and maintained by a unique mechanism. In fission yeast, Eso1p, functioning in close coupling to DNA replication, establishes sister chromatid cohesion whereas the newly identified Cohesin-associated protein Pds5p hinders the establishment of cohesion until counteracted by Eso1p, yet stabilizes cohesion once it is established. Eso1p interacts physically with Pds5p via its Ctf7p/Eco1p-homologous domain.

Entities: Chemical Gene Species

Mesh：

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Year: 2001 PMID： 11598020 PMCID： PMC125673 DOI： 10.1093/emboj/20.20.5779

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

51 in total

Review 1. Splitting the chromosome: cutting the ties that bind sister chromatids.

Authors: K Nasmyth; J M Peters; F Uhlmann
Journal: Science Date: 2000-05-26 Impact factor: 47.728

Review 2. Sister chromatid cohesion: the beginning of a long and beautiful relationship.

Authors: D E Koshland; V Guacci
Journal: Curr Opin Cell Biol Date: 2000-06 Impact factor: 8.382

3. Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus.

Authors: P Geck; J Szelei; J Jimenez; C Sonnenschein; A M Soto
Journal: J Steroid Biochem Mol Biol Date: 1999-01 Impact factor: 4.292

Establishment and maintenance of sister chromatid cohesion in fission yeast by a unique mechanism.

Review 1. Splitting the chromosome: cutting the ties that bind sister chromatids.

Review 2. Sister chromatid cohesion: the beginning of a long and beautiful relationship.

3. Early gene expression during androgen-induced inhibition of proliferation of prostate cancer cells: a new suppressor candidate on chromosome 13, in the BRCA2-Rb1 locus.

Review 4. Cell cycle mechanisms of sister chromatid separation; roles of Cut1/separin and Cut2/securin.

5. Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae.

6. Fission yeast Eso1p is required for establishing sister chromatid cohesion during S phase.

7. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe.

8. Pol kappa: A DNA polymerase required for sister chromatid cohesion.

9. Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins.

10. Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes.

1. Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60.

Review 2. From a single double helix to paired double helices and back.

3. Pds5 promotes cohesin acetylation and stable cohesin-chromosome interaction.

Review 4. Sister acts: coordinating DNA replication and cohesion establishment.

Review 5. A cohesin-based structural platform supporting homologous chromosome pairing in meiosis.

6. Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.

7. Releasing cohesin from chromosome arms in early mitosis: opposing actions of Wapl-Pds5 and Sgo1.

Review 8. Roles of the sister chromatid cohesion apparatus in gene expression, development, and human syndromes.

9. Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

10. Fission yeast Sap1 protein is essential for chromosome stability.