| Literature DB >> 11597410 |
M Sedlák1, V Buchta, L Kubicová, P Simůnek, M Holcapek, P Kasparová.
Abstract
The reaction of methoxypoly(ethylene glycol)-4-nitrophenyl carbonate with amphotericin B has been used to prepare a new conjugate of amphotericin B (mPEG-AmB). A preliminary screening of in vitro antifungal activity has suggested that mPEG-AmB possesses a similar effect and a similar spectrum of activity as the conventional amphotericin B formulated with sodium desoxycholate.Entities:
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Year: 2001 PMID： 11597410 DOI： 10.1016/s0960-894x(01)00532-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823