| Literature DB >> 1159684 |
H Zimmer, R Glaser, J Kokosa, D A Garteiz, E V Hess, A Litwin.
Abstract
The elucidation of the structure of a new major metabolic product of hydralazine, 3-hydroxymethyl-s-triazolo[3,4-a]-phthalazine, is described. The structures of several other previously described metabolites of the drug, phthalazone, s-triazolo[3,4-a]phthalazine, and 3-methyl-s-triazolo[3,4-a]phthalazine, are confirmed. A metabolic pathway of hydralazine is also proposed.Entities:
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Year: 1975 PMID： 1159684 DOI： 10.1021/jm00244a018
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446