Literature DB >> 11594640

The effects of increased rehabilitation therapy after brain injury: results of a prospective controlled trial.

A Shiel1, J P Burn, D Henry, J Clark, B A Wilson, M E Burnett, D L McLellan.   

Abstract

OBJECTIVE: The objective was to investigate the effect of increased intensity of rehabilitation therapy provided to brain-injured subjects on the rate at which independence was regained and the duration of hospital admission.
DESIGN: A two-centre, prospective, controlled study with random allocation to groups.
SETTING: Two district general hospitals on the south coast of England.
SUBJECTS: Fifty-six people with moderate and severe head injury consecutively admitted to Southampton and Poole hospitals between June 1995 and September 1997.
INTERVENTIONS: Increased intensity of rehabilitation therapy input without change in content.
RESULTS: Subjects receiving more intensive therapy made more rapid progress and were discharged home sooner. The different intensities of therapy employed in this study showed no evidence of a 'ceiling' effect and the 'intervention group' made significantly more rapid progress on tests of dependency during the period of admission. A clear response to increased therapy input was seen in one of the centres with more rapid functional improvement and a shorter length of hospital stay. This centre already had more therapy and better community facilities. No such benefits were seen at the other centre where the intervention group had a longer hospital stay than the routine group.
CONCLUSION: Increasing the hours per week of therapy given to adults recovering from brain injury in hospital can accelerate the rate of recovery of personal independence and result in their being discharged from hospital sooner. Increased rehabilitation therapy after brain injury is associated with enhanced functional recovery and shorter hospital stay if provided in the context of an integrated service that can provide ongoing community support. There is no evidence of any ceiling effect of therapeutic intensity beyond which no further response is observed.

Entities:  

Mesh:

Year:  2001        PMID: 11594640     DOI: 10.1191/026921501680425225

Source DB:  PubMed          Journal:  Clin Rehabil        ISSN: 0269-2155            Impact factor:   3.477


  26 in total

1.  Evaluation of a combined treatment paradigm consisting of environmental enrichment and the 5-HT1A receptor agonist buspirone after experimental traumatic brain injury.

Authors:  Anthony E Kline; Adam S Olsen; Christopher N Sozda; Ann N Hoffman; Jeffrey P Cheng
Journal:  J Neurotrauma       Date:  2012-05-21       Impact factor: 5.269

2.  A relatively brief exposure to environmental enrichment after experimental traumatic brain injury confers long-term cognitive benefits.

Authors:  Jeffrey P Cheng; Kaitlyn E Shaw; Christina M Monaco; Ann N Hoffman; Christopher N Sozda; Adam S Olsen; Anthony E Kline
Journal:  J Neurotrauma       Date:  2012-08-27       Impact factor: 5.269

3.  Abbreviated environmental enrichment enhances neurobehavioral recovery comparably to continuous exposure after traumatic brain injury.

Authors:  Benjamin Wells de Witt; Kathryn M Ehrenberg; Rose L McAloon; Amanda H Panos; Kaitlyn E Shaw; Priya V Raghavan; Elizabeth R Skidmore; Anthony E Kline
Journal:  Neurorehabil Neural Repair       Date:  2010-12-26       Impact factor: 3.919

4.  The effect of environmental enrichment on substantia nigra gene expression after traumatic brain injury in rats.

Authors:  Samuel S Shin; James W Bales; Hong Q Yan; Anthony E Kline; Amy K Wagner; James Lyons-Weiler; C Edward Dixon
Journal:  J Neurotrauma       Date:  2013-02-05       Impact factor: 5.269

5.  Environmental enrichment as a viable neurorehabilitation strategy for experimental traumatic brain injury.

Authors:  Corina O Bondi; Kyle C Klitsch; Jacob B Leary; Anthony E Kline
Journal:  J Neurotrauma       Date:  2014-04-17       Impact factor: 5.269

Review 6.  Biologic and plastic effects of experimental traumatic brain injury treatment paradigms and their relevance to clinical rehabilitation.

Authors:  Alexandra N Garcia; Mansi A Shah; C Edward Dixon; Amy K Wagner; Anthony E Kline
Journal:  PM R       Date:  2011-06       Impact factor: 2.298

Review 7.  Found in translation: Understanding the biology and behavior of experimental traumatic brain injury.

Authors:  Corina O Bondi; Bridgette D Semple; Linda J Noble-Haeusslein; Nicole D Osier; Shaun W Carlson; C Edward Dixon; Christopher C Giza; Anthony E Kline
Journal:  Neurosci Biobehav Rev       Date:  2014-12-10       Impact factor: 8.989

8.  Abbreviated environmental enrichment confers neurobehavioral, cognitive, and histological benefits in brain-injured female rats.

Authors:  Hannah L Radabaugh; Lauren J Carlson; Darik A O'Neil; Megan J LaPorte; Christina M Monaco; Jeffrey P Cheng; Patricia B de la Tremblaye; Naima Lajud; Corina O Bondi; Anthony E Kline
Journal:  Exp Neurol       Date:  2016-09-28       Impact factor: 5.330

9.  The Therapeutic Efficacy of Environmental Enrichment and Methylphenidate Alone and in Combination after Controlled Cortical Impact Injury.

Authors:  Jacob B Leary; Corina O Bondi; Megan J LaPorte; Lauren J Carlson; Hannah L Radabaugh; Jeffrey P Cheng; Anthony E Kline
Journal:  J Neurotrauma       Date:  2016-05-09       Impact factor: 5.269

10.  Development and initial validation of the Northwick Park Therapy Dependency Assessment.

Authors:  Lynne Turner-Stokes; Asa Shaw; Janet Law; Hilary Rose
Journal:  Clin Rehabil       Date:  2009-10       Impact factor: 3.477

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