Literature DB >> 11591944

A randomized controlled trial to determine the effect of humidified carbon dioxide (CO2) insufflation on postoperative pain following thoracoscopic procedures.

W G Mouton1, M Naef, J R Bessell, K T Otten, H E Wagner, G J Maddern.   

Abstract

BACKGROUND: It has previously been shown that the insufflation of humidified gas during laparoscopy results in less postoperative pain than is observed following the use of dry gas. Experimental evidence also suggests that dry gas insufflation during thoracoscopy results in greater structural injury to the pleura than occurs with the use of humidified gas. The present study was designed to determine the effect of humidified gas insufflation on postoperative pain following thoracoscopic procedures.
METHODS: Forty consecutive patients were prospectively randomized. Twenty patients were insufflated with humidified carbon dioxide (CO(2)), and 20 control patients received standard dry CO(2).
RESULTS: The patients' analogue pain score was significantly lower following humidified gas insufflation compared to dry gas insufflation when assessed at 6 h postoperatively, as well as on the 1st, 2nd, 3rd, and 14th postoperative days. The postoperative morphine consumption was lower in the humidified group than it was in the control group. The incidence of respiratory complications was identical for both groups.
CONCLUSION: The use of humidified gas appears to reduce postoperative pain but not the rate of respiratory complications.

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Year:  2001        PMID: 11591944     DOI: 10.1007/s004640090055

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  4 in total

1.  Warmed, humidified carbon dioxide insufflation versus standard carbon dioxide in laparoscopic cholecystectomy: a double-blinded randomized controlled trial.

Authors:  Bettina Klugsberger; Markus Schreiner; Alexander Rothe; Dietmar Haas; Peter Oppelt; Andreas Shamiyeh
Journal:  Surg Endosc       Date:  2014-04-23       Impact factor: 4.584

2.  Intraperitoneal aerosolization of bupivacaine reduces postoperative pain in laparoscopic surgery: a randomized prospective controlled double-blinded clinical trial.

Authors:  N A Alkhamesi; D H Peck; D Lomax; A W Darzi
Journal:  Surg Endosc       Date:  2006-12-16       Impact factor: 4.584

3.  Intraperitoneal aerosolization of bupivacaine is a safe and effective method in controlling postoperative pain in laparoscopic Roux-en-Y gastric bypass.

Authors:  Nawar A Alkhamesi; James M Kane; Paul J Guske; Jonathan W Wallace; Peter C Rantis
Journal:  J Pain Res       Date:  2008-12-01       Impact factor: 3.133

Review 4.  Humidification during laparoscopic surgery: overview of the clinical benefits of using humidified gas during laparoscopic surgery.

Authors:  Maria Mercedes Binda
Journal:  Arch Gynecol Obstet       Date:  2015-04-25       Impact factor: 2.344

  4 in total

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