| Literature DB >> 11589918 |
E Vanmechelen1, H Vanderstichele, F Hulstaert, N Andreasen, L Minthon, B Winblad, P Davidsson, K Blennow.
Abstract
The reliability of cerebrospinal fluid (CSF)-tau and CSF-beta-amyloid assays for diagnosis of Alzheimer's disease and other dementing disorders such as frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and Creutzfeldt-Jakob disease (CJD) is reviewed. CSF assessment of the two proteins is useful in early diagnosis of AD and to differentiate it from FTD and DLB. Extremely high CSF-tau levels can discriminate CJD from AD.Entities:
Mesh:
Substances:
Year: 2001 PMID: 11589918 DOI: 10.1016/s0047-6374(01)00304-9
Source DB: PubMed Journal: Mech Ageing Dev ISSN: 0047-6374 Impact factor: 5.432