Literature DB >> 115898

Characterization of a screening test for diphtherial toxin antigen produced by individual plaques of corynebacteriophages.

S L Welkos, R K Holmes.   

Abstract

A passive immune hemolysis assay has been developed to detect diphtherial toxin produced in individual plaques of tox+ corynebacteriophages. This assay permits rapid screening of large numbers of corynebacteriophages for their ability to code for diphtherial toxin or related antigens. The specificity of the assay and its potential usefulness for genetic studies of toxinogenesis have been demonstrated with well-characterized tox+ and tox- laboratory strains of corynebacteriophages.

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Year:  1979        PMID： 115898      PMCID： PMC275381          DOI： 10.1128/jcm.9.6.693-698.1979

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  28 in total

1.  Cell culture reactivity to diphtheria, Staphylococcus, tetanus and Escherichia coli toxins.

Authors:  J GABLIKS; M SOLOTOROVSKY
Journal:  J Immunol       Date:  1962-04       Impact factor: 5.422

2.  A simple chromatographic method for preparation of gamma globulin.

Authors:  H B LEVY; H A SOBER
Journal:  Proc Soc Exp Biol Med       Date:  1960-01

3.  Antigenic analysis by diffusion.

Authors:  C L OAKLEY; A J FULTHORPE
Journal:  J Pathol Bacteriol       Date:  1953-01

Review 4.  Diphtheria toxin: mode of action and structure.

Authors:  R J Collier
Journal:  Bacteriol Rev       Date:  1975-03

5.  The recognition of toxicogenic bacterial strains in vitro.

Authors:  S D ELEK
Journal:  Br Med J       Date:  1948-03-13

6.  Further studies on the in vitro test for virulence of Corynebacterium diphtheriae.

Authors:  E O KING; M FROBISHER; E I PARSONS
Journal:  Am J Public Health Nations Health       Date:  1950-06

Review 7.  Diphtheria toxin.

Authors:  A M Pappenheimer
Journal:  Annu Rev Biochem       Date:  1977       Impact factor: 23.643

8.  Mutations of corynephage beta that affect the yield of diphtheria toxin.

Authors:  T Uchida; C Kanei; M Yoneda
Journal:  Virology       Date:  1977-04       Impact factor: 3.616

9.  Radial passive immune hemolysis assay for detection of heat-labile enterotoxin produced by individual colonies of Escherichia coli or Vibrio cholerae.

Authors:  M G Bramucci; R K Holmes
Journal:  J Clin Microbiol       Date:  1978-08       Impact factor: 5.948

10.  The effect of diphtheria toxin on the metabolism of HeLa cells.

Authors:  N STRAUSS; E D HENDEE
Journal:  J Exp Med       Date:  1959-02-01       Impact factor: 14.307
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  5 in total

1.  Genetic and biochemical evidence for a siderophore-dependent iron transport system in Corynebacterium diphtheriae.

Authors:  L M Russell; S J Cryz; R K Holmes
Journal:  Infect Immun       Date:  1984-07       Impact factor: 3.441

2.  Highly toxinogenic but avirulent Park-Williams 8 strain of Corynebacterium diphtheriae does not produce siderophore.

Authors:  L M Russell; R K Holmes
Journal:  Infect Immun       Date:  1985-02       Impact factor: 3.441

3.  Regulation of toxinogenesis in Corynebacterium diphtheriae. II. Genetic mapping of a tox regulatory mutation in bacteriophage beta.

Authors:  S L Welkos; R K Holmes
Journal:  J Virol       Date:  1981-03       Impact factor: 5.103

4.  Regulation of toxinogenesis in Corynebacterium diphtheriae. I. Mutations in bacteriophage beta that alter the effects of iron on toxin production.

Authors:  S L Welkos; R K Holmes
Journal:  J Virol       Date:  1981-03       Impact factor: 5.103

5.  Regulation of toxinogenesis in Corynebacterium diphtheriae: mutations in the bacterial genome that alter the effects of iron on toxin production.

Authors:  S J Cryz; L M Russell; R K Holmes
Journal:  J Bacteriol       Date:  1983-04       Impact factor: 3.490
  5 in total

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