| Literature DB >> 11589773 |
S Kase1, G Shiota, Y Fujii, K Okamoto, K Oyama, T Nakano, T Nomura, T Suou, K Nakashima, H Ito, H Kawasaki.
Abstract
The case of a 77-year-old woman with hepatitis C virus infection with a 5-year history of muscle weakness and mild disturbance of gait is reported. Steroid therapy did not improve her symptoms. She developed HCV-related liver cirrhosis and hepatocellular carcinoma, and muscle biopsy revealed inclusion body myositis. Immunohistochemistry showed that the nonstructural region of HCV and 8-hydroxy-2'-deoxyguanosine, a marker of DNA damage by reactive oxygen species, were present in striated muscle cells of this patient.Entities:
Mesh：
Year: 2001 PMID： 11589773 DOI： 10.1034/j.1600-0676.2001.210509.x
Source DB: PubMed Journal: Liver ISSN： 0106-9543