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Literature DB >> 11587475

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential--toward a consensus.

G T Tucker¹, J B Houston, S M Huang.

Abstract

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Year: 2001 PMID： 11587475 DOI： 10.1023/a:1010994022294

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

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19 in total

1. Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions.

Authors: John T Barr; Jeffrey P Jones
Journal: Drug Metab Dispos Date: 2011-09-22 Impact factor: 3.922

2. The use of wireless laptop computers for computer-assisted learning in pharmacokinetics.

Authors: Myrna Y Munar; Harleen Singh; Donna Belle; Carolyn C Brackett; Sandra B Earle
Journal: Am J Pharm Educ Date: 2006-02-15 Impact factor: 2.047

Review 3. The effect of St John's wort extracts on CYP3A: a systematic review of prospective clinical trials.

Authors: D L Whitten; S P Myers; J A Hawrelak; H Wohlmuth
Journal: Br J Clin Pharmacol Date: 2006-09-29 Impact factor: 4.335

4. The effect of Shoseiryuto, a traditional Japanese medicine, on cytochrome P450s, N-acetyltransferase 2 and xanthine oxidase, in extensive or intermediate metabolizers of CYP2D6.

Authors: Masashi Nakao; Yousuke Muramoto; Motoko Hisadome; Naoko Yamano; Mami Shoji; Yumi Fukushima; Junji Saruwatari; Kazuko Nakagawa
Journal: Eur J Clin Pharmacol Date: 2007-02-13 Impact factor: 2.953

10. Effect of nanonization on absorption of 301029: ex vivo and in vivo pharmacokinetic correlations determined by liquid chromatography/mass spectrometry.

Authors: Lee Jia; Hong Wong; Cesario Cerna; Steve D Weitman
Journal: Pharm Res Date: 2002-08 Impact factor: 4.200

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential--toward a consensus.

1. Inhibition of human liver aldehyde oxidase: implications for potential drug-drug interactions.

2. The use of wireless laptop computers for computer-assisted learning in pharmacokinetics.

Review 3. The effect of St John's wort extracts on CYP3A: a systematic review of prospective clinical trials.

4. The effect of Shoseiryuto, a traditional Japanese medicine, on cytochrome P450s, N-acetyltransferase 2 and xanthine oxidase, in extensive or intermediate metabolizers of CYP2D6.

5. Interspecies pharmacokinetics and in vitro metabolism of SQ109.

6. Identification of enzymes involved in phase I metabolism of ciclesonide by human liver microsomes.

Review 7. The conduct of drug metabolism studies considered good practice (II): in vitro experiments.

8. The quantitative prediction of CYP-mediated drug interaction by physiologically based pharmacokinetic modeling.

9. Evaluation of flurbiprofen urinary ratios as in vivo indices for CYP2C9 activity.

10. Effect of nanonization on absorption of 301029: ex vivo and in vivo pharmacokinetic correlations determined by liquid chromatography/mass spectrometry.