Literature DB >> 11585677

Knockout models resulting in the development of obesity.

A A Butler1, R D Cone.   

Abstract

Our understanding of body weight regulation has been greatly advanced by the characterization of previously existing mutations in mice that cause obesity. Subsequent analysis of a number of mouse knockout models has greatly expanded the number of genes known to influence adiposity by affecting metabolic rate, physical activity, and/or appetite.

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Year:  2001        PMID： 11585677     DOI： 10.1016/s0168-9525(01)02481-7

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  11 in total

1.  Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor.

Authors:  Erica J P Anderson; Masoud Ghamari-Langroudi; Isin Cakir; Michael J Litt; Valerie Chen; Roman E Reggiardo; Glenn L Millhauser; Roger D Cone
Journal:  J Neuroendocrinol       Date:  2019-01-20       Impact factor: 3.627

2.  Computational gene expression modeling identifies salivary biomarker analysis that predict oral feeding readiness in the newborn.

Authors:  Jill L Maron; Jooyeon S Hwang; Subash Pathak; Robin Ruthazer; Ruby L Russell; Gil Alterovitz
Journal:  J Pediatr       Date:  2015-02       Impact factor: 4.406

3.  Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists.

Authors:  Zoe M Koerperich; Mark D Ericson; Katie T Freeman; Robert C Speth; Irina D Pogozheva; Henry I Mosberg; Carrie Haskell-Luevano
Journal:  J Med Chem       Date:  2020-01-06       Impact factor: 7.446

4.  Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome.

Authors:  D S Sinasac; J D Riordan; S H Spiezio; B S Yandell; C M Croniger; J H Nadeau
Journal:  Int J Obes (Lond)       Date:  2015-09-18       Impact factor: 5.095

Review 5.  Obesity surgery: happy with less or eternally hungry?

Authors:  Andrew C Shin; Hans-Rudolf Berthoud
Journal:  Trends Endocrinol Metab       Date:  2013-01-11       Impact factor: 12.015

6.  Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17.

Authors:  Carrie A Millward; Lindsay C Burrage; Haifeng Shao; David S Sinasac; Jean H Kawasoe; Annie E Hill-Baskin; Sheila R Ernest; Aga Gornicka; Chang-Wen Hsieh; Sorana Pisano; Joseph H Nadeau; Colleen M Croniger
Journal:  Mamm Genome       Date:  2009-01-10       Impact factor: 2.957

7.  Neuropeptide Y2 receptor (NPY2R) expression in saliva predicts feeding immaturity in the premature neonate.

Authors:  Jill L Maron; Kirby L Johnson; Jessica A Dietz; Minghua L Chen; Diana W Bianchi
Journal:  PLoS One       Date:  2012-05-21       Impact factor: 3.240

8.  Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade.

Authors:  Michael B Mumphrey; Zheng Hao; R Leigh Townsend; Laurel M Patterson; Christopher D Morrison; Heike Münzberg; Nicholas Stylopoulos; Jianping Ye; Hans-Rudolf Berthoud
Journal:  Obesity (Silver Spring)       Date:  2014-05-02       Impact factor: 5.002

9.  Whole-Body ARHGAP21-Deficiency Improves Energetic Homeostasis in Lean and Obese Mice.

Authors:  Gabriela Moreira Soares; Lucas Zangerolamo; Jose Maria Costa-Júnior; Jean Franciesco Vettorazzi; Everardo Magalhães Carneiro; Sara Teresinha Saad; Antonio Carlos Boschero; Helena Cristina Barbosa-Sampaio
Journal:  Front Endocrinol (Lausanne)       Date:  2019-05-29       Impact factor: 5.555

10.  Identification of G Protein-Coupled Receptors (GPCRs) in Primary Cilia and Their Possible Involvement in Body Weight Control.

Authors:  Yoshihiro Omori; Taro Chaya; Satoyo Yoshida; Shoichi Irie; Toshinori Tsujii; Takahisa Furukawa
Journal:  PLoS One       Date:  2015-06-08       Impact factor: 3.240
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