Literature DB >> 11585670

Transgenic mouse models of Alzheimer's disease.

B J Hock1, B T Lamb.   

Abstract

Recent advances in the understanding of the genetic basis of Alzheimer's disease have enabled the production of transgenic mouse models of the disease. Utilizing both cDNA- and genomic-based approaches, these mouse models for Alzheimer's disease have already provided valuable insights into the pathogenesis of the disease and potential therapeutic interventions.

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Year:  2001        PMID： 11585670     DOI： 10.1016/s0168-9525(01)02449-0

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  21 in total

Review 1.  Usefulness of behavioral and electrophysiological studies in transgenic models of Alzheimer's disease.

Authors:  Antonino Sant'Angelo; Fabrizio Trinchese; Ottavio Arancio
Journal:  Neurochem Res       Date:  2003-07       Impact factor: 3.996

Review 2.  APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD).

Authors:  R Lalonde; K Fukuchi; C Strazielle
Journal:  Neurosci Biobehav Rev       Date:  2012-02-21       Impact factor: 8.989

3.  Amyloid deposition and advanced age fails to induce Alzheimer's type progression in a double knock-in mouse model.

Authors:  Gauri H Malthankar-Phatak; Yin-Guo Lin; Nicholas Giovannone; Robert Siman
Journal:  Aging Dis       Date:  2011-07-28       Impact factor: 6.745

Review 4.  Divide and die: cell cycle events as triggers of nerve cell death.

Authors:  Karl Herrup; Rachael Neve; Susan L Ackerman; Agata Copani
Journal:  J Neurosci       Date:  2004-10-20       Impact factor: 6.167

5.  Cell cycle activation and CNS injury.

Authors:  Bogdan A Stoica; Kimberly R Byrnes; Alan I Faden
Journal:  Neurotox Res       Date:  2009-04-21       Impact factor: 3.911

Review 6.  The case for rejecting the amyloid cascade hypothesis.

Authors:  Karl Herrup
Journal:  Nat Neurosci       Date:  2015-06       Impact factor: 24.884

7.  The benefits and limitations of animal models for translational research in neurodegenerative diseases.

Authors:  Mathias Jucker
Journal:  Nat Med       Date:  2010-09-21       Impact factor: 53.440

Review 8.  Geriatric syndromes: clinical, research, and policy implications of a core geriatric concept.

Authors:  Sharon K Inouye; Stephanie Studenski; Mary E Tinetti; George A Kuchel
Journal:  J Am Geriatr Soc       Date:  2007-05       Impact factor: 5.562

9.  Evidences for B6C3-Tg (APPswe/PSEN1dE9) double-transgenic mice between 3 and 10 months as an age-related Alzheimer's disease model.

Authors:  Zhiyong Zhong; Lin Yang; Xiansheng Wu; Wei Huang; Jiarong Yan; Shenglai Liu; Xia Sun; Ke Liu; Huangquan Lin; Shaosong Kuang; Xiaojiang Tang
Journal:  J Mol Neurosci       Date:  2013-12-21       Impact factor: 3.444

Review 10.  TGF-β1 pathway as a new target for neuroprotection in Alzheimer's disease.

Authors:  Filippo Caraci; Giuseppe Battaglia; Valeria Bruno; Paolo Bosco; Viviana Carbonaro; Maria Laura Giuffrida; Filippo Drago; Maria Angela Sortino; Ferdinando Nicoletti; Agata Copani
Journal:  CNS Neurosci Ther       Date:  2009-11-19       Impact factor: 5.243
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