Literature DB >> 11584981

Anticholinergic effects of medication in elderly patients.

L E Tune1.   

Abstract

Anticholinergic toxicity is a common problem in the elderly. It has many effects ranging from dry mouth, constipation, and visual impairments to confusion, delirium, and severe cognitive decline. The toxicity is often the result of the cumulative anticholinergic burden of multiple prescription medications and metabolites rather than of a single compound. The management of elderly patients, particularly those suffering from dementia, should therefore aim to reduce the use of medications with anticholinergic effects.

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Year:  2001        PMID: 11584981

Source DB:  PubMed          Journal:  J Clin Psychiatry        ISSN: 0160-6689            Impact factor:   4.384


  106 in total

Review 1.  Delirium: an important (but often unrecognized) clinical syndrome.

Authors:  Terry Rabinowitz
Journal:  Curr Psychiatry Rep       Date:  2002-06       Impact factor: 5.285

Review 2.  Behavior-analytic research on dementia in older adults.

Authors:  Maranda A Trahan; SungWoo Kahng; Alyssa B Fisher; Nicole L Hausman
Journal:  J Appl Behav Anal       Date:  2011

3.  Prevalence and predictors of anticholinergic medication use in elderly nursing home residents with dementia: analysis of data from the 2004 National Nursing Home Survey.

Authors:  Satabdi Chatterjee; Sandhya Mehta; Jeffrey T Sherer; Rajender R Aparasu
Journal:  Drugs Aging       Date:  2010-12-01       Impact factor: 3.923

Review 4.  Safety and tolerability profiles of anticholinergic agents used for the treatment of overactive bladder.

Authors:  Michael G Oefelein
Journal:  Drug Saf       Date:  2011-09-01       Impact factor: 5.606

Review 5.  Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder.

Authors:  Paul Abrams; Karl-Erik Andersson; Jerry J Buccafusco; Christopher Chapple; William Chet de Groat; Alison D Fryer; Gary Kay; Alan Laties; Neil M Nathanson; Pankaj Jay Pasricha; Alan J Wein
Journal:  Br J Pharmacol       Date:  2006-06-05       Impact factor: 8.739

6.  Cevimeline hydrochloride improved cholinergic dysfunction in a patient with pure autonomic failure.

Authors:  Atsushi Ogata; Masayasu Kitano; Hajime Sano
Journal:  J Neurol       Date:  2005-07-05       Impact factor: 4.849

7.  Managing polypharmacy in a 77-year-old woman with multiple prescribers.

Authors:  Barbara Farrell; Véronique French Merkley; Wade Thompson
Journal:  CMAJ       Date:  2013-07-15       Impact factor: 8.262

8.  Relation Between Delirium and Anticholinergic Drug Burden in a Cohort of Hospitalized Older Patients: An Observational Study.

Authors:  Luca Pasina; Lorenzo Colzani; Laura Cortesi; Mauro Tettamanti; Antonella Zambon; Alessandro Nobili; Andrea Mazzone; Paolo Mazzola; Giorgio Annoni; Giuseppe Bellelli
Journal:  Drugs Aging       Date:  2019-01       Impact factor: 3.923

9.  Concomitant medications and possible side effects of antimuscarinic agents.

Authors:  Scott A Macdiarmid
Journal:  Rev Urol       Date:  2008

10.  Dual use of bladder anticholinergics and cholinesterase inhibitors: long-term functional and cognitive outcomes.

Authors:  Kaycee M Sink; Joseph Thomas; Huiping Xu; Bruce Craig; Steven Kritchevsky; Laura P Sands
Journal:  J Am Geriatr Soc       Date:  2008-04-01       Impact factor: 5.562

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