Literature DB >> 11584280

Presenilins and the intramembrane proteolysis of proteins: facts and fiction.

B D Strooper1, W Annaert.   

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Year:  2001        PMID: 11584280     DOI: 10.1038/ncb1001-e221

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN: 1465-7392            Impact factor:   28.824


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  11 in total

1.  Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.

Authors:  Heiko Runz; Jens Rietdorf; Inge Tomic; Marina de Bernard; Konrad Beyreuther; Rainer Pepperkok; Tobias Hartmann
Journal:  J Neurosci       Date:  2002-03-01       Impact factor: 6.167

2.  Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation.

Authors:  Dieter Edbauer; Edith Winkler; Christian Haass; Harald Steiner
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-04       Impact factor: 11.205

3.  A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish.

Authors:  Andrea Geling; Harald Steiner; Michael Willem; Laure Bally-Cuif; Christian Haass
Journal:  EMBO Rep       Date:  2002-07       Impact factor: 8.807

4.  Dependency of γ-secretase complex activity on the structural integrity of the bilayer.

Authors:  Hua Zhou; Shuxia Zhou; Peter J Walian; Bing K Jap
Journal:  Biochem Biophys Res Commun       Date:  2010-10-16       Impact factor: 3.575

5.  CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.

Authors:  Shuxia Zhou; Hua Zhou; Peter J Walian; Bing K Jap
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-12       Impact factor: 11.205

6.  The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms.

Authors:  Xuefeng Xia; Pei Wang; Xiaoyan Sun; Salvador Soriano; Wan-Kyng Shum; Haruyasu Yamaguchi; Myrna E Trumbauer; Akihiko Takashima; Edward H Koo; Hui Zheng
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-17       Impact factor: 11.205

7.  Gamma-secretase: substrates and inhibitors.

Authors:  Marjorie J Rochette; M Paul Murphy
Journal:  Mol Neurobiol       Date:  2002-08       Impact factor: 5.590

8.  Positive and negative regulation of APP amyloidogenesis by sumoylation.

Authors:  Yonghong Li; Hui Wang; Su Wang; Diana Quon; Yu-Wang Liu; Barbara Cordell
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-27       Impact factor: 11.205

9.  HPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?

Authors:  Tae Hyuk Kang; Ghiabe-Henri Guibinga; H A Jinnah; Theodore Friedmann
Journal:  PLoS One       Date:  2011-01-28       Impact factor: 3.240

Review 10.  The role of proteases in regulating Eph/ephrin signaling.

Authors:  Lakmali Atapattu; Martin Lackmann; Peter W Janes
Journal:  Cell Adh Migr       Date:  2014       Impact factor: 3.405

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