Literature DB >> 11582551

Geranins C and D, additional new antiprotozoal A-type proanthocyanidins from Geranium niveum.

F Calzada, R Cedillo-Rivera, R Bye, R Mata.   

Abstract

Two new additional A-type proanthocyanidins have been isolated from Geranium niveum. Their structures were determined by spectroscopic, chemical and chiroptical methods as epi-afzelechin-(4beta-->8,2beta-->O-->7)-gallocatechin (1) and epi-afzelechin-(4beta-->8,2beta-->O-->7)-afzelechin-(4beta-->8,2beta-->O-->7)-afzelechin (2). Proanthocyanidins 1 and 2 were given the trivial names of geranins C and D, respectively. Compound 2 showed moderate antiprotozoal activity against Entamoeba histolytica and Giardia lamblia, whereas 1 exhibited weak activity toward E. histolytica.

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Year:  2001        PMID： 11582551     DOI： 10.1055/s-2001-17358

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  7 in total

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Journal:  Front Cell Infect Microbiol       Date:  2018-06-22       Impact factor: 5.293

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6.  Hesperidin identified from Citrus extracts potently inhibits HCV genotype 3a NS3 protease.

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7.  Multidimensional in silico strategy for identification of natural polyphenols-based SARS-CoV-2 main protease (Mpro) inhibitors to unveil a hope against COVID-19.

Authors:  Şevki Adem; Volkan Eyupoglu; Ibrahim M Ibrahim; Iqra Sarfraz; Azhar Rasul; Muhammad Ali; Abdo A Elfiky
Journal:  Comput Biol Med       Date:  2022-03-26       Impact factor: 6.698
  7 in total

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