Literature DB >> 11582526

[Pelvic type of chronic recurrent multifocal osteomyelitis].

F Schilling1, W Coerdt, A Eckardt, H Full, T Hospach, S Kessler, M Köcher, K F Kreitner.   

Abstract

We report about the juvenile and adolescent pelvic type of CRMO in 7 girls and 4 boys. The results show from solitary up to 7 pelvic lesions (average 3 lesions) predominantly in the acetabular and paraacetabular region (sometimes with hip joint effusion as a sign for concomitant coxitis).Tc99m-bone-scan is helpful to evaluate exactly the pattern of bone affection. We find 3 stages of an primarily chronic, non-purulent osteomyelitis going along with a "plasma-cell-sclerotic process", leading to a Garrè-type sclerosing end-stage, which probably heals after some years spontaneously, projecting on clinical symptoms and radiological appearance. The concomitant coxitis ("sympathetic coxitis") is clinically often in the foreground, but reversible. Pain in case of CRMO responds surprisingly well on medication with acithromycine. Knowing about CRMO in its different clinical appearances - especially concerning what we call "sympathetic coxitis" - can be a useful for pediatric rheumatologists and orthopedic surgeons, as well as MRI-focused radiologists and pathologists. Therapy might find a useful drug in acithromycine. In conclusion we d like to point out, that CRMO is one entity under the "roof" of the so called SAPHO-syndrome, which again shows us, that SAPHO-syndrome ist not a diagnosis itself but more a sign-post on the way to a correct diagnosis.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11582526     DOI: 10.1055/s-2001-17219

Source DB:  PubMed          Journal:  Klin Padiatr        ISSN: 0300-8630            Impact factor:   1.349


  3 in total

1.  [SAPHO syndrome. A contribution to discussion].

Authors:  Fritz Schilling
Journal:  Wien Klin Wochenschr       Date:  2003-02-28       Impact factor: 1.704

2.  Chronic non-bacterial osteomyelitis in children.

Authors:  H J Girschick; P Raab; S Surbaum; A Trusen; S Kirschner; P Schneider; T Papadopoulos; H K Müller-Hermelink; P E Lipsky
Journal:  Ann Rheum Dis       Date:  2005-02       Impact factor: 19.103

3.  [SAPHO syndrome : An overview and nosological differentiation of 35 disease cases].

Authors:  Philipp Klemm; Uwe Lange
Journal:  Z Rheumatol       Date:  2021-03-16       Impact factor: 1.372

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.