Literature DB >> 11580059

The use of a neutralizing monoclonal antibody to detect infections of equine herpesvirus type 2 (EHV-2).

A Nordengrahn1, B Klingeborn, A Lindholm, M Merza.   

Abstract

A blocking enzyme-linked immunosorbent assay (ELISA) was developed to detect antibodies to equine herpesvirus 2 in serum samples of horses. By measuring the binding to a single epitope, this blocking ELISA gives a good picture of the antibody status in the animal. The test is based on a monoclonal antibody with neutralizing activity and had a sensitivity of 94% and a specificity of 100%. Antibodies due to newly acquired infection in foals were successfully detected with this blocking ELISA.

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Year:  2001        PMID: 11580059     DOI: 10.1177/104063870101300504

Source DB:  PubMed          Journal:  J Vet Diagn Invest        ISSN: 1040-6387            Impact factor:   1.279


  3 in total

1.  Equine herpesvirus 2 (EHV-2) infection in thoroughbred horses in Argentina.

Authors:  María I Craig; María E Barrandeguy; Fernando M Fernández
Journal:  BMC Vet Res       Date:  2005-11-09       Impact factor: 2.741

Review 2.  Gammaherpesvirus infections in equids: a review.

Authors:  Maria Luisa Marenzoni; Valentina Stefanetti; Maria Luisa Danzetta; Peter Joseph Timoney
Journal:  Vet Med (Auckl)       Date:  2015-04-01

3.  The effect of maternal immunity on the equine gammaherpesvirus type 2 and 5 viral load and antibody response.

Authors:  Lilja Thorsteinsdóttir; Sigríður Jónsdóttir; Sara Björk Stefánsdóttir; Valgerður Andrésdóttir; Bettina Wagner; Eliane Marti; Sigurbjörg Torsteinsdóttir; Vilhjálmur Svansson
Journal:  PLoS One       Date:  2019-06-21       Impact factor: 3.240

  3 in total

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