Literature DB >> 11579259

Variation in breastmilk HIV-1 viral load in left and right breasts during the first 3 months of lactation.

J F Willumsen1, M L Newell, S M Filteau, A Coutsoudis, S Dwarika, D York, A M Tomkins, H M Coovadia.   

Abstract

The mechanism and risk factors associated with mother-to-child transmission of HIV-1 through breastfeeding remain unclear; breastmilk viral load may be an important determinant of transmission. Analysis of breastmilk cell-free viral load in samples taken from each breast at 1, 6 and 14 weeks postpartum showed that HIV-1 is shed intermittently and load may differ considerably between breasts of an individual woman at any given time. Breastmilk HIV-1 load was undetectable in approximately one-third of samples.

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Year:  2001        PMID： 11579259     DOI： 10.1097/00002030-200109280-00026

Source DB:  PubMed          Journal:  AIDS        ISSN： 0269-9370            Impact factor:   4.177


  8 in total

1.  Differential innate immune responses to low or high dose oral SIV challenge in Rhesus macaques.

Authors:  Andre Durudas; Hui-Ling Chen; Melanie A Gasper; Vasudha Sundaravaradan; Jeffrey M Milush; Guido Silvestri; Welkin Johnson; Luis D Giavedoni; Donald L Sodora
Journal:  Curr HIV Res       Date:  2011-07       Impact factor: 1.581

2.  Post-weaning breast milk HIV-1 viral load, blood prolactin levels and breast milk volume.

Authors:  Donald M Thea; Grace Aldrovandi; Chipepo Kankasa; Prisca Kasonde; W Donald Decker; Katherine Semrau; Moses Sinkala; Louise Kuhn
Journal:  AIDS       Date:  2006-07-13       Impact factor: 4.177

3.  HIV-1 concentrations in human breast milk before and after weaning.

Authors:  Louise Kuhn; Hae-Young Kim; Jan Walter; Donald M Thea; Moses Sinkala; Mwiya Mwiya; Chipepo Kankasa; Don Decker; Grace M Aldrovandi
Journal:  Sci Transl Med       Date:  2013-04-17       Impact factor: 17.956

Review 4.  Breast-feeding and Transmission of HIV-1.

Authors:  Grace John-Stewart; Dorothy Mbori-Ngacha; Rene Ekpini; Edward N Janoff; John Nkengasong; Jennifer S Read; Phillippe Van de Perre; Marie-Louise Newell
Journal:  J Acquir Immune Defic Syndr       Date:  2004-02-01       Impact factor: 3.731

5.  Temporal and lateral dynamics of HIV shedding and elevated sodium in breast milk among HIV-positive mothers during the first 4 months of breast-feeding.

Authors:  Katherine Semrau; Mrinal Ghosh; Chipepo Kankasa; Moses Sinkala; Prisca Kasonde; Mwiya Mwiya; Donald M Thea; Louise Kuhn; Grace M Aldrovandi
Journal:  J Acquir Immune Defic Syndr       Date:  2008-03-01       Impact factor: 3.731

6.  Cumulative exposure to cell-free HIV in breast milk, rather than feeding pattern per se, identifies postnatally infected infants.

Authors:  Dorine Neveu; Johannes Viljoen; Ruth M Bland; Nicolas Nagot; Siva Danaviah; Anna Coutsoudis; Nigel Campbell Rollins; Hoosen M Coovadia; Philippe Van de Perre; Marie-Louise Newell
Journal:  Clin Infect Dis       Date:  2011-03-15       Impact factor: 9.079

7.  The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk.

Authors:  Tatenda Mahlokozera; Helen H Kang; Nilu Goonetilleke; Andrea R Stacey; Rachel V Lovingood; Thomas N Denny; Linda Kalilani; James E G Bunn; Steve R Meshnick; Persephone Borrow; Norman L Letvin; Sallie R Permar
Journal:  PLoS One       Date:  2011-08-23       Impact factor: 3.240

8.  Cell-free (RNA) and cell-associated (DNA) HIV-1 and postnatal transmission through breastfeeding.

Authors:  James Ndirangu; Johannes Viljoen; Ruth M Bland; Siva Danaviah; Claire Thorne; Philippe Van de Perre; Marie-Louise Newell
Journal:  PLoS One       Date:  2012-12-28       Impact factor: 3.240
  8 in total

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