Literature DB >> 1157871

A central nervous system depressant-antidepressant.

A P Roszkowski, M E Schuler, M Mark, J A Edwards.   

Abstract

A new tricyclic agent with an allenyl side chain experimentally shows antidepressant activity similar to amitriptyline and imipramine but also exerts marked CNS depression. Such dual activity should be of clinical interest for treatment of mixed anxiety and depression.

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Year:  1975        PMID: 1157871     DOI: 10.1007/bf02358877

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  7 in total

1.  A SIMPLE SCREENING PROCEDURE FOR IMIPRAMINE-LIKE ANTIDEPRESSANT AGENTS.

Authors:  B M ASKEW
Journal:  Life Sci (1962)       Date:  1963-10

2.  A simplified method of evaluating dose-effect experiments.

Authors:  J T LITCHFIELD; F WILCOXON
Journal:  J Pharmacol Exp Ther       Date:  1949-06       Impact factor: 4.030

3.  Uses of psychotherapeutic drugs.

Authors:  L E Hollister
Journal:  Ann Intern Med       Date:  1973-07       Impact factor: 25.391

4.  Psychotropic drugs in use today. The role of diazepam in medical practice.

Authors:  B Blackwell
Journal:  JAMA       Date:  1973-09-24       Impact factor: 56.272

5.  A comparative trial of imipramine and phenobarbital in depressed patients seen in general practice.

Authors:  D Wheatley
Journal:  J Nerv Ment Dis       Date:  1969-05       Impact factor: 2.254

6.  Anxiety, depression and psychotropic drugs.

Authors:  L E Hollister
Journal:  Drugs       Date:  1971       Impact factor: 9.546

7.  Comparison of chlordiazepoxide-amitriptyline combination with amitriptyline alone in anxiety-depressive states.

Authors:  H P Hare
Journal:  J Clin Pharmacol New Drugs       Date:  1971 Nov-Dec
  7 in total

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