Literature DB >> 11577996

Establishment of a consistent L929 bioassay system for TNF-alpha quantitation to evaluate the effect of lipopolysaccharide, phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-alpha secreted by adherent human mononuclear cells.

M Y Shiau1, H L Chiou, Y L Lee, T M Kuo, Y H Chang.   

Abstract

TUMOR necrosis factor-alpha (TNF-alpha) plays an important role in the pathogenesis of rheumatoid arthritis. The present study was to evaluate the effects of lipopolysaccharide (LPS), phytomitogens and cytodifferentiation agents on cytotoxicity of TNF-alpha secreted by adherent human mononuclear cells (AMC). TNF-alpha cytotoxicity in LPS-treated, phytomitogen-treated, and cytodifferentiation agent-treated AMC supernatants were analyzed by the L929 bioassay system. Our results showed that LPS could induce homogeneous TNF-alpha production by AMC whereas, in addition to TNF-alpha, phytomitogens could also induce other TNF-like factors. Neither methotrexate, retinoic acid nor sodium butyrate can inhibit TNF-alpha cytotoxicity, while hexamethylene bisacetamide could not only inhibit TNF-alpha cytotoxicity but also TNF-alpha inducing ability of LPS to AMC.

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Year:  2001        PMID： 11577996      PMCID： PMC1781708          DOI： 10.1080/09629350123139

Source DB:  PubMed          Journal:  Mediators Inflamm        ISSN： 0962-9351            Impact factor:   4.711


  20 in total

1.  Inhibition of neutrophil chemotaxis in methotrexate-treated rheumatoid arthritis patients.

Authors:  J W O'Callaghan; M J Forrest; P M Brooks
Journal:  Rheumatol Int       Date:  1988       Impact factor: 2.631

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Journal:  J Immunol Methods       Date:  1986-12-04       Impact factor: 2.303

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Journal:  J Immunol Methods       Date:  1984-03-30       Impact factor: 2.303

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Authors:  T Mosmann
Journal:  J Immunol Methods       Date:  1983-12-16       Impact factor: 2.303

Review 5.  New insights into the pathogenesis of rheumatoid arthritis.

Authors:  C M Weyand
Journal:  Rheumatology (Oxford)       Date:  2000-06       Impact factor: 7.580

6.  Immunologic studies of rheumatoid arthritis patients treated with methotrexate.

Authors:  N J Olsen; L F Callahan; T Pincus
Journal:  Arthritis Rheum       Date:  1987-05

7.  Activation of human polymorphonuclear neutrophil functions by interferon-gamma and tumor necrosis factors.

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Journal:  J Immunol       Date:  1985-09       Impact factor: 5.422

8.  Efficacy of low-dose methotrexate in rheumatoid arthritis.

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Journal:  N Engl J Med       Date:  1985-03-28       Impact factor: 91.245

9.  Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro.

Authors:  B J Sugarman; B B Aggarwal; P E Hass; I S Figari; M A Palladino; H M Shepard
Journal:  Science       Date:  1985-11-22       Impact factor: 47.728

10.  Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

Authors:  J M Dayer; B Beutler; A Cerami
Journal:  J Exp Med       Date:  1985-12-01       Impact factor: 14.307
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  13 in total

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Authors:  Baowei Su; Arzu Cengizeroglu; Katarina Farkasova; Joana R Viola; Martina Anton; Joachim W Ellwart; Rudolf Haase; Ernst Wagner; Manfred Ogris
Journal:  Mol Ther       Date:  2012-11-13       Impact factor: 11.454

2.  Shiga toxin 1-induced inflammatory response in lipopolysaccharide-sensitized astrocytes is mediated by endogenous tumor necrosis factor alpha.

Authors:  Verónica I Landoni; Marcelo de Campos-Nebel; Pablo Schierloh; Cecilia Calatayud; Gabriela C Fernandez; M Victoria Ramos; Bárbara Rearte; Marina S Palermo; Martín A Isturiz
Journal:  Infect Immun       Date:  2009-12-14       Impact factor: 3.441

3.  Role of TNF-α in the mechanisms responsible for preterm delivery induced by Stx2 in rats.

Authors:  Juliana Burdet; Flavia Sacerdoti; Maximiliano Cella; Ana M Franchi; Cristina Ibarra
Journal:  Br J Pharmacol       Date:  2013-02       Impact factor: 8.739

4.  Long-term exposure to monoclonal anti-TNF is associated with an increased risk of lymphoma in BAFF-transgenic mice.

Authors:  Gaetane Nocturne; Bineta Ly; Audrey Paoletti; Juliette Pascaud; Raphaele Seror; Carole Nicco; Fabienne Mackay; F B Vincent; Thierry Lazure; Sophie Ferlicot; Lev Stimmer; Quentin Pascal; Sandrine Roulland; Roman Krzysiek; Salima Hacein-Bey; Frederic Batteux; Xavier Mariette
Journal:  Clin Exp Immunol       Date:  2021-05-30       Impact factor: 5.732

5.  Transmembrane TNF-dependent uptake of anti-TNF antibodies.

Authors:  Arun Deora; Subramanya Hegde; Jacqueline Lee; Chee-Ho Choi; Qing Chang; Cheryl Lee; Lucia Eaton; Hua Tang; Dongdong Wang; David Lee; Mark Michalak; Medha Tomlinson; Qingfeng Tao; Nidhi Gaur; Bohdan Harvey; Shaun McLoughlin; Boris Labkovsky; Tariq Ghayur
Journal:  MAbs       Date:  2017-03-21       Impact factor: 5.857

6.  Erratum to "Establishment of a Consistent L929 Bioassay System for TNF-α Quantitation to Evaluate the Effect of Lipopolysaccharide, Phytomitogens and Cytodifferentiation Agents on Cytotoxicity of TNF-α Secreted by Adherent Human Mononuclear Cells".

Authors:  Ming-Yuh Shiau; Hui-Ling Chiou; Yao-Ling Lee; Tzer-Min Kuo; Yih-Hsin Chang
Journal:  Mediators Inflamm       Date:  2017-03-16       Impact factor: 4.711

7.  The synthetic melanocortin (CKPV)2 exerts anti-fungal and anti-inflammatory effects against Candida albicans vaginitis via inducing macrophage M2 polarization.

Authors:  Hai-xia Ji; Yu-lian Zou; Jing-jing Duan; Zhi-rong Jia; Xian-jing Li; Zhuo Wang; Li Li; Yong-wen Li; Gen-yan Liu; Ming-qing Tong; Xiao-yi Li; Guo-hui Zhang; Xiang-rong Dai; Ling He; Zhi-yu Li; Cong Cao; Yong Yang
Journal:  PLoS One       Date:  2013-02-14       Impact factor: 3.240

8.  Impact of neutrophil-secreted myeloid related proteins 8 and 14 (MRP 8/14) on leishmaniasis progression.

Authors:  Irazú Contreras; Marina T Shio; Annabelle Cesaro; Philippe A Tessier; Martin Olivier
Journal:  PLoS Negl Trop Dis       Date:  2013-09-26

9.  High Level Expression and Purification of Recombinant Proteins from Escherichia coli with AK-TAG.

Authors:  Dan Luo; Caixia Wen; Rongchuan Zhao; Xinyu Liu; Xinxin Liu; Jingjing Cui; Joshua G Liang; Peng Liang
Journal:  PLoS One       Date:  2016-05-23       Impact factor: 3.240

10.  Autocrine Tnf signaling favors malignant cells in myelofibrosis in a Tnfr2-dependent fashion.

Authors:  William L Heaton; Anna V Senina; Anthony D Pomicter; Mohamed E Salama; Phillip M Clair; Dongqing Yan; Russell N Bell; Jeremy M Gililland; Josef T Prchal; Thomas O'Hare; Michael W Deininger
Journal:  Leukemia       Date:  2018-04-18       Impact factor: 11.528
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