Literature DB >> 1157717

[Effectiveness of subcutaneous heparin in the prevention of thrombo-embolism after major hip operations (author's transl)].

T H Schöndorf, D Hey.   

Abstract

Low doses of heparin were administered subcutaneously to 103 patients starting the evening before major hip operations, while a further 95 were given calcium heparinate, starting the night after operation in conventional high doses. No anticoagulants were given to 27 patients who served as controls. In none of the patients given anticoagulants was there an increased incidence of postoperative wound complications. But the rate of thrombo-embolism was significantly reduced among those on conventional high doses of heparin. The rate of thromboembolism was also reduced among those on the lower dosage (compared with the control subjects), but this form of prophylaxis was not as effective for patients especially at risk.

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Year:  1975        PMID: 1157717     DOI: 10.1055/s-0028-1106493

Source DB:  PubMed          Journal:  Dtsch Med Wochenschr        ISSN: 0012-0472            Impact factor:   0.628


  3 in total

Review 1.  Anticoagulants versus non-steroidal anti-inflammatories or placebo for treatment of venous thromboembolism.

Authors:  D K Cundiff; J Manyemba; J C Pezzullo
Journal:  Cochrane Database Syst Rev       Date:  2006-01-25

2.  [Clinical and in-vitro studies of the therapeutical range of acetylsalicylic-acid to prevent deep vein thrombosis (author's transl)].

Authors:  T H Schöndorf; D Hey; H G Lasch
Journal:  Klin Wochenschr       Date:  1978-11-15

Review 3.  Clinical pharmacokinetics of heparin.

Authors:  J W Estes
Journal:  Clin Pharmacokinet       Date:  1980 May-Jun       Impact factor: 6.447

  3 in total

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