| Literature DB >> 11575945 |
I S Chen1, H F Chen, M J Cheng, Y L Chang, C M Teng, I Tsutomu, J J Chen, I L Tsai.
Abstract
Three new quinoline alkaloids, 2-acetylevolitrine (1), 2-acetylpteleine (2), and semecarpifoline (3), along with 26 known compounds were isolated from the root bark of Melicope semecarpifolia. The structures of 1-3 were elucidated by means of spectral analysis. In addition, (2S)-(--)-7,8-dimethoxyplatydesmine (4), cis-(+)-7,8-dimethoxymyrtopsine (5), and (3R)-(--)-8,9-dimethoxygeibalansine (6) were isolated as new natural products. Several of these isolates were determined as exhibiting significant antiplatelet aggregation activities in vitro.Entities:
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Year: 2001 PMID： 11575945 DOI： 10.1021/np010122k
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050