Literature DB >> 11571943

Surgeon's occupational exposure to nitrous oxide and sevoflurane during pediatric surgery.

C Byhahn1, K Heller, V Lischke, K Westphal.   

Abstract

Health hazards from occupational exposure to trace concentrations of anaesthetic gases cannot be definitively excluded. The aim of the study was to determine the surgeon's occupational exposure to nitrous oxide and sevoflurane during pediatric surgical procedures. Twenty young children (age < 10 years) and five teenagers (age > 10 years) underwent elective abdominal surgery under general inhalational anesthesia. The operating room was equipped with modern air conditioning and waste anesthetic gas scavenger. Levels of both nitrous oxide and sevoflurane were determined in the breathing zone of the surgeon and the anesthesiologist during the operative procedures by means of a direct-reading photoacoustic infrared spectrometer. Both the surgeon and the anesthesiologist were exposed to low concentrations of the inhalational agents used. Exposure to sevoflurane and nitrous oxide was clearly higher during surgery in young children than during operative procedures in teenagers. Nonetheless, the concentrations of these agents were well below the threshold limits of 25 ppm for nitrous oxide and 2 ppm for sevoflurane recommended by the National Institute of Occupational Safety and Health. General anesthesia results in operating room air pollution with inhalational anesthetics. Under modern air conditioning, personnel's occupational exposure is low, and inhalational anesthesia is safe from the standpoint of modern workplace laws and health care regulations. Nonetheless, all efforts must be taken to maintain occupational exposure at this low level.

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Year:  2001        PMID: 11571943     DOI: 10.1007/bf03215855

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  21 in total

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Journal:  N Engl J Med       Date:  1969-03-06       Impact factor: 91.245

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Journal:  Environ Mol Mutagen       Date:  1996       Impact factor: 3.216

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Authors:  A S Rowland; D D Baird; D L Shore; C R Weinberg; D A Savitz; A J Wilcox
Journal:  Am J Epidemiol       Date:  1995-03-15       Impact factor: 4.897

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  7 in total

Review 1.  Occupational exposure to volatile anaesthetics: epidemiology and approaches to reducing the problem.

Authors:  C Byhahn; H J Wilke; K Westpphal
Journal:  CNS Drugs       Date:  2001       Impact factor: 5.749

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Authors:  F Schiewe-Langgartner; G Wiesner; M Gruber; J Hobbhahn
Journal:  Anaesthesist       Date:  2005-07       Impact factor: 1.041

3.  DNA damage and repair after exposure to sevoflurane in vivo, evaluated in Swiss albino mice by the alkaline comet assay and micronucleus test.

Authors:  G Brozovic; N Orsolic; R Rozgaj; V Kasuba; F Knezevic; A H Knezevic; V Benkovic; D Lisicic; N Borojevic; D Dikic
Journal:  J Appl Genet       Date:  2010       Impact factor: 3.240

4.  Multi-capillary column-ion mobility spectrometry (MCC-IMS) as a new method for the quantification of occupational exposure to sevoflurane in anaesthesia workplaces: an observational feasibility study.

Authors:  Nils Kunze; Cathrin Weigel; Wolfgang Vautz; Katrin Schwerdtfeger; Melanie Jünger; Michael Quintel; Thorsten Perl
Journal:  J Occup Med Toxicol       Date:  2015-03-27       Impact factor: 2.646

5.  Photoacoustic gas monitoring for anesthetic gas pollution measurements and its cross-sensitivity to alcoholic disinfectants.

Authors:  Jennifer Herzog-Niescery; Thomas Steffens; Martin Bellgardt; Andreas Breuer-Kaiser; Philipp Gude; Heike Vogelsang; Thomas Peter Weber; Hans-Martin Seipp
Journal:  BMC Anesthesiol       Date:  2019-08-09       Impact factor: 2.217

6.  Effects of sevoflurane exposure on apoptosis and cell cycle of peripheral blood lymphocytes, and immunologic function.

Authors:  Zhimin Ji; Wanjun Wu; Fan Zhou; Junfang Hu; Qiuping Xu; Weibin Yang; Xueyong Peng; Xinguo Wang; Cheng Zhang; Li Li
Journal:  BMC Anesthesiol       Date:  2021-03-20       Impact factor: 2.217

7.  Firstborn offspring sex ratio is skewed towards female offspring in anesthesia care providers: A questionnaire-based nationwide study from United States.

Authors:  Deepak Gupta; Edward Kaminski; George McKelvey; Hong Wang
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2013-04
  7 in total

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