Literature DB >> 11571227

Molecular pathogenesis of the von Hippel-Lindau hereditary cancer syndrome: implications for oxygen sensing.

H Yang1, W G Kaelin.   

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Year:  2001        PMID: 11571227

Source DB:  PubMed          Journal:  Cell Growth Differ        ISSN: 1044-9523


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  11 in total

1.  Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.

Authors:  Nianli Sang; Jie Fang; Vickram Srinivas; Irene Leshchinsky; Jaime Caro
Journal:  Mol Cell Biol       Date:  2002-05       Impact factor: 4.272

2.  von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination.

Authors:  Anna V Kuznetsova; Jaroslaw Meller; Phillip O Schnell; James A Nash; Monika L Ignacak; Yolanda Sanchez; Joan W Conaway; Ronald C Conaway; Maria F Czyzyk-Krzeska
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-25       Impact factor: 11.205

3.  USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer.

Authors:  Haibiao Xie; Jin Zhou; Xijuan Liu; Yawei Xu; Austin J Hepperla; Jeremy M Simon; Tao Wang; Hongwei Yao; Chengheng Liao; Albert S Baldwin; Kan Gong; Qing Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2022-08-29       Impact factor: 12.779

4.  Molecular pathology and CXCR4 expression in surgically excised retinal hemangioblastomas associated with von Hippel-Lindau disease.

Authors:  Xiaoling Liang; Defen Shen; Yongsheng Huang; Chunyue Yin; Christine M Bojanowski; Zhengping Zhuang; Chi-Chao Chan
Journal:  Ophthalmology       Date:  2006-10-27       Impact factor: 12.079

5.  Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

Authors:  Christine C Hudson; Mei Liu; Gary G Chiang; Diane M Otterness; Dawn C Loomis; Fiona Kaper; Amato J Giaccia; Robert T Abraham
Journal:  Mol Cell Biol       Date:  2002-10       Impact factor: 4.272

6.  USP37 promotes deubiquitination of HIF2α in kidney cancer.

Authors:  Kai Hong; Lianxin Hu; Xijuan Liu; Jeremy M Simon; Travis S Ptacek; Xingnan Zheng; Chengheng Liao; Albert S Baldwin; Qing Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2020-05-27       Impact factor: 11.205

7.  Caspase processing activates atypical protein kinase C zeta by relieving autoinhibition and destabilizes the protein.

Authors:  Lucinda Smith; Zhi Wang; Jeffrey B Smith
Journal:  Biochem J       Date:  2003-11-01       Impact factor: 3.857

8.  A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation.

Authors:  Xiaoyu Lin; Caroline A David; Jennifer B Donnelly; Mike Michaelides; Navdeep S Chandel; Xiaoli Huang; Usha Warrior; Frank Weinberg; Kathryn V Tormos; Stephen W Fesik; Yu Shen
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-02       Impact factor: 11.205

9.  TBK1 Is a Synthetic Lethal Target in Cancer with VHL Loss.

Authors:  Lianxin Hu; Haibiao Xie; Xijuan Liu; Frances Potjewyd; Lindsey I James; Emily M Wilkerson; Laura E Herring; Ling Xie; Xian Chen; Johnny Castillo Cabrera; Kai Hong; Chengheng Liao; Xianming Tan; Albert S Baldwin; Kan Gong; Qing Zhang
Journal:  Cancer Discov       Date:  2019-12-06       Impact factor: 38.272

Review 10.  VHL and Hypoxia Signaling: Beyond HIF in Cancer.

Authors:  Jing Zhang; Qing Zhang
Journal:  Biomedicines       Date:  2018-03-19
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