Literature DB >> 11570120

Exercise as hypertension therapy.

P F Kokkinos1, P Narayan, V Papademetriou.   

Abstract

In conclusion, the findings of most recent studies show that moderate-intensity aerobic exercise training can lower BP in patients with stage 1 and 2 essential hypertension. The average reduction in BP is 10.5 mm Hg for systolic and 7.6 mm Hg for diastolic BP. The reductions do not appear to be gender- or age-specific. Significant reductions in BP and LVH regression in patients with stage 3 hypertension have also been reported following aerobic exercise training. Resistance training exercise has not consistently shown to significantly lower BP and is not recommended as the only form of exercise for hypertensive patients. The exercise training program for optimal benefits should consist of 3 to 5 times per week, 30 to 60 minutes per session, at 50% to 80% of PMHR. However, exercise programs should be individualized to meet the patient's needs and abilities. Exercise intensity and duration should be manipulated to promote a safe and effective antihypertensive program. Initially, the exercise intensity should be low and the duration short. Both intensity and duration should progressive increase over a period of weeks until the desired goal, is achieved. The rate of progression must be tailored to meet individual patient needs and abilities. The exercise program for overweight or obese hypertensive patients should aim to promote a caloric expenditure of 300 to 500 Kcal per day and 1000 to 2000 Kcal per week. Such an approach, combined with a prudent diet, is likely to reduce body weight. The mechanisms mediating exercise-induced BP reduction are poorly understood. BP reductions appear to be independent of changes in body weight or body composition. There are also no indications of age- or gender-related differences in BP response to exercise. The use of ambulatory blood pressure measuring devices in exercise studies is not extensive. The few studies available indicate a more moderate reduction in BP than that reported by casual observations.

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Year:  2001        PMID: 11570120     DOI: 10.1016/s0733-8651(05)70232-0

Source DB:  PubMed          Journal:  Cardiol Clin        ISSN: 0733-8651            Impact factor:   2.213


  14 in total

1.  [Instrument for the assessment of middle-aged and older adults' physical activity: design, eliability and application of the German-PAQ-50+].

Authors:  Christina Huy; Sven Schneider
Journal:  Z Gerontol Geriatr       Date:  2008-03-11       Impact factor: 1.281

2.  Exercise prevents leptin-induced increase in blood pressure in Sprague-Dawley rats.

Authors:  K Farhana; I Effendi; Brinnell Caszo; Nuraliza Abdul Satar; H J Singh
Journal:  J Physiol Biochem       Date:  2014-04-08       Impact factor: 4.158

3.  Effect of exercise training volume on arterial contractility and BK(Ca) channel activity in rat thoracic aorta smooth muscle cells.

Authors:  Lijun Shi; Li Zhao; Fanxing Zeng; Na Li; Xiaodong Liu
Journal:  Eur J Appl Physiol       Date:  2012-02-17       Impact factor: 3.078

Review 4.  Lifestyle interventions for cardiovascular risk reduction in women with breast cancer.

Authors:  M Tish Knobf; Jessica Coviello
Journal:  Curr Cardiol Rev       Date:  2011-11

5.  Physical inactivity and mortality risk.

Authors:  Peter Kokkinos; Helen Sheriff; Raya Kheirbek
Journal:  Cardiol Res Pract       Date:  2011-01-20       Impact factor: 1.866

6.  Moderate Treadmill Exercise Training Improves Cardiovascular and Nitrergic Response and Resistance to Trypanosoma cruzi Infection in Mice.

Authors:  Bruno F C Lucchetti; Nágela G Zanluqui; Hiviny de Ataides Raquel; Maria I Lovo-Martins; Vera L H Tatakihara; Mônica de Oliveira Belém; Lisete C Michelini; Eduardo J de Almeida Araújo; Phileno Pinge-Filho; Marli C Martins-Pinge
Journal:  Front Physiol       Date:  2017-05-18       Impact factor: 4.566

Review 7.  Skeletal muscle as an endocrine organ: PGC-1α, myokines and exercise.

Authors:  Svenia Schnyder; Christoph Handschin
Journal:  Bone       Date:  2015-11       Impact factor: 4.398

8.  Physical activity, health benefits, and mortality risk.

Authors:  Peter Kokkinos
Journal:  ISRN Cardiol       Date:  2012-10-30

9.  Physical activity, sex, and socioeconomic status: A population based study.

Authors:  Mohammad Talaei; Katayoun Rabiei; Zahra Talaei; Negar Amiri; Behzad Zolfaghari; Payam Kabiri; Nizal Sarrafzadegan
Journal:  ARYA Atheroscler       Date:  2013-01

10.  Effect of mild aerobic training on the myocardium of mice with chronic Chagas disease.

Authors:  Emerson Preto; Nathalia Ea Lima; Lucila Simardi; Fernando Luiz Affonso Fonseca; Abílio Augusto Fragata Filho; Laura Beatriz Mesiano Maifrino
Journal:  Biologics       Date:  2015-09-23
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