Literature DB >> 11566349

Detection of a novel t(6;15)(q21;q21) in a pediatric Wilms tumor.

C V Fernandez1, V S Lestou, J Wildish, C L Lee, P H Sorensen.   

Abstract

We report a novel cytogenetic finding in a favorable histology Wilms tumor occurring in a 4-month-old boy. Karyotypic analysis demonstrated a t(6;15)(q21;q21) in all tumor cells examined. This was confirmed using fluorescence in situ hybridization analysis. Molecular analysis of this rearrangement may provide clues to understanding the pathobiology of Wilms tumor.

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Year:  2001        PMID： 11566349     DOI： 10.1016/s0165-4608(01)00445-9

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  6 in total

1.  Bayesian Cox Proportional Hazards Model in Survival Analysis of HACE1 Gene with Age at Onset of Alzheimer's Disease.

Authors:  Ke-Sheng Wang; Ying Liu; Shaoqing Gong; Chun Xu; Xin Xie; Liang Wang; Xingguang Luo
Journal:  Int J Clin Biostat Biom       Date:  2017-12-01

2.  A novel loss-of-function mutation in HACE1 is linked to a genetic disorder in a patient from India.

Authors:  Nivedita Hariharan; Samathmika Ravi; Bulagonda Eswarappa Pradeep; Koushik Narayan Subramanyam; Bibha Choudhary; Subhashini Srinivasan; Prakash Khanchandani
Journal:  Hum Genome Var       Date:  2018-02-08

3.  HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.

Authors:  Busra Turgu; Fan Zhang; Amal El-Naggar; Gian Luca Negri; Melanie Kogler; Luigi Tortola; Fraser Johnson; Tony Ng; Amy Li; Donald Yapp; William Lockwood; Daniel Martinez; John M Maris; Mads Daugaard; Josef M Penninger; Christopher S Hughes; Poul H Sorensen
Journal:  Oncogene       Date:  2021-02-18       Impact factor: 9.867

4.  Lin28 promotes transformation and is associated with advanced human malignancies.

Authors:  Srinivas R Viswanathan; John T Powers; William Einhorn; Yujin Hoshida; Tony L Ng; Sara Toffanin; Maureen O'Sullivan; Jun Lu; Letha A Phillips; Victoria L Lockhart; Samar P Shah; Pradeep S Tanwar; Craig H Mermel; Rameen Beroukhim; Mohammad Azam; Jose Teixeira; Matthew Meyerson; Timothy P Hughes; Josep M Llovet; Jerald Radich; Charles G Mullighan; Todd R Golub; Poul H Sorensen; George Q Daley
Journal:  Nat Genet       Date:  2009-05-31       Impact factor: 38.330

5.  Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome.

Authors:  Saba F Ali; Rebecca J Sonu; Denis M Dwyre; Brian A Jonas; Hooman H Rashidi
Journal:  Case Rep Hematol       Date:  2015-12-21

6.  Physiopathological Bases of the Disease Caused by HACE1 Mutations: Alterations in Autophagy, Mitophagy and Oxidative Stress Response.

Authors:  Olatz Ugarteburu; Marta Sánchez-Vilés; Julio Ramos; Tamara Barcos-Rodríguez; Gloria Garrabou; Judit García-Villoria; Antonia Ribes; Frederic Tort
Journal:  J Clin Med       Date:  2020-03-26       Impact factor: 4.241
  6 in total

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