Literature DB >> 11564436

Role of IL-10 in allergen-specific immunotherapy and normal response to allergens.

C A Akdis1, K Blaser.   

Abstract

Induction of specific unresponsiveness (tolerance/anergy) in peripheral T cells by interleukin-10 (IL-10) and recovery by cytokines from the tissue microenvironment represent two key steps in specific immunotherapy of allergy and in natural exposure to allergens in healthy individuals. IL-10 elicits anergy in T cells by selective inhibition of the CD28 costimulatory pathway and controls suppression and development of antigen-specific immunity.

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Year:  2001        PMID： 11564436     DOI： 10.1016/s1286-4579(01)01449-6

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  12 in total

Review 1.  IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage.

Authors:  Anne O'Garra; Pedro L Vieira; Paulo Vieira; Anne E Goldfeld
Journal:  J Clin Invest       Date:  2004-11       Impact factor: 14.808

2.  Use of multiple peptides containing T cell epitopes is a feasible approach for peptide-based immunotherapy in Can f 1 allergy.

Authors:  Anu K Immonen; Antti H Taivainen; Ale T O Närvänen; Tuure T Kinnunen; Soili A Saarelainen; Marja A Rytkönen-Nissinen; Tuomas I Virtanen
Journal:  Immunology       Date:  2007-01       Impact factor: 7.397

3.  Oral glucocorticoid treatment decreases interleukin-10 receptor expression on peripheral blood leucocyte subsets.

Authors:  M Moniuszko; A Bodzenta-Lukaszyk; M Dabrowska
Journal:  Clin Exp Immunol       Date:  2009-03-09       Impact factor: 4.330

Review 4.  Pathophysiology of autoimmune pancreatitis.

Authors:  Raffaele Pezzilli; Nico Pagano
Journal:  World J Gastrointest Pathophysiol       Date:  2014-02-15

5.  DGKα DNA vaccine relieves airway allergic inflammation in asthma model possibly via induction of T cell anergy.

Authors:  Yan Wang; Qiao Zhang; Qianli Ma; Youlan Zhang; Zhiwei Li; Changzheng Wang
Journal:  Int J Clin Exp Pathol       Date:  2013-10-15

6.  Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3).

Authors:  Aleena Syed; Marco A Garcia; Shu-Chen Lyu; Robert Bucayu; Arunima Kohli; Satoru Ishida; Jelena P Berglund; Mindy Tsai; Holden Maecker; Gerri O'Riordan; Stephen J Galli; Kari C Nadeau
Journal:  J Allergy Clin Immunol       Date:  2014-02       Impact factor: 10.793

7.  Allergen-specific subcutaneous immunotherapy in allergic asthma: immunologic mechanisms and improvement.

Authors:  Yousef A Taher; Paul A J Henricks; Antoon J M van Oosterhout
Journal:  Libyan J Med       Date:  2010-06-21       Impact factor: 1.657

8.  A novel method of modifying immune responses by vaccination with lipiodol-siRNA mixtures.

Authors:  Thomas E Ichim; Igor A Popov; Neil H Riordan; Hamid Izadi; Zaohui Zhong; Li Yijian; Salman Sher; Eugenia K Oleinik
Journal:  J Transl Med       Date:  2006-01-03       Impact factor: 5.531

9.  Tolerogenic dendritic cells derived from donors with natural rubber latex allergy modulate allergen-specific T-cell responses and IgE production.

Authors:  Alejandro Escobar; Adam Aguirre; María Antonieta Guzmán; Rodrigo González; Diego Catalán; Claudio Acuña-Castillo; Milton Larrondo; Mercedes López; Barbara Pesce; Jennifer Rolland; Robyn O'Hehir; Juan Carlos Aguillón
Journal:  PLoS One       Date:  2014-01-22       Impact factor: 3.240

Review 10.  Primary atopic disorders.

Authors:  Jonathan J Lyons; Joshua D Milner
Journal:  J Exp Med       Date:  2018-03-16       Impact factor: 14.307
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